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Age-Related Psychophysiological Vulnerability to Phenylalanine in Phenylketonuria

Overview of attention for article published in Frontiers in Pediatrics, June 2014
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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1 X user
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1 peer review site

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22 Mendeley
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Title
Age-Related Psychophysiological Vulnerability to Phenylalanine in Phenylketonuria
Published in
Frontiers in Pediatrics, June 2014
DOI 10.3389/fped.2014.00057
Pubmed ID
Authors

Vincenzo Leuzzi, Daniela Mannarelli, Filippo Manti, Caterina Pauletti, Nicoletta Locuratolo, Carla Carducci, Claudia Carducci, Nicola Vanacore, Francesco Fattapposta

Abstract

Phenylketonuria (PKU) is caused by the inherited defect of the phenylalanine hydroxylase enzyme, which converts phenylalanine (Phe) into tyrosine (Tyr). Neonatal screening programs and early treatment have radically changed the natural history of PKU. Nevertheless, an increased risk of neurocognitive and psychiatric problems in adulthood remains a challenging aspect of the disease. In order to assess the vulnerability of complex skills to Phe, we explored: (a) the effect of a rapid increase in blood Phe levels on event-related potentials (ERP) in PKU subjects during their second decade of life; (b) the association (if existing) between psychophysiological and neurocognitive features.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 36%
Student > Ph. D. Student 3 14%
Other 2 9%
Student > Master 2 9%
Researcher 2 9%
Other 2 9%
Unknown 3 14%
Readers by discipline Count As %
Medicine and Dentistry 9 41%
Psychology 3 14%
Materials Science 2 9%
Neuroscience 2 9%
Agricultural and Biological Sciences 1 5%
Other 2 9%
Unknown 3 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 June 2014.
All research outputs
#14,197,145
of 22,757,541 outputs
Outputs from Frontiers in Pediatrics
#2,040
of 5,916 outputs
Outputs of similar age
#120,179
of 228,089 outputs
Outputs of similar age from Frontiers in Pediatrics
#15
of 37 outputs
Altmetric has tracked 22,757,541 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,916 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,089 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.