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Rethinking Molecular Mimicry in Rheumatic Heart Disease and Autoimmune Myocarditis: Laminin, Collagen IV, CAR, and B1AR as Initial Targets of Disease

Overview of attention for article published in Frontiers in Pediatrics, August 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

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4 X users

Citations

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37 Dimensions

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39 Mendeley
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Title
Rethinking Molecular Mimicry in Rheumatic Heart Disease and Autoimmune Myocarditis: Laminin, Collagen IV, CAR, and B1AR as Initial Targets of Disease
Published in
Frontiers in Pediatrics, August 2014
DOI 10.3389/fped.2014.00085
Pubmed ID
Authors

Robert Root-Bernstein

Abstract

Molecular mimicry theory (MMT) suggests that epitope mimicry between pathogens and human proteins can activate autoimmune disease. Group A streptococci (GAS) mimics human cardiac myosin in rheumatic heart disease (RHD) and coxsackie viruses (CX) mimic actin in autoimmune myocarditis (AM). But myosin and actin are immunologically inaccessible and unlikely initial targets. Extracellular cardiac proteins that mimic GAS and CX would be more likely.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 15%
Student > Bachelor 6 15%
Student > Doctoral Student 4 10%
Other 4 10%
Student > Master 4 10%
Other 6 15%
Unknown 9 23%
Readers by discipline Count As %
Medicine and Dentistry 9 23%
Agricultural and Biological Sciences 8 21%
Biochemistry, Genetics and Molecular Biology 7 18%
Immunology and Microbiology 4 10%
Social Sciences 1 3%
Other 1 3%
Unknown 9 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2023.
All research outputs
#14,430,214
of 24,620,113 outputs
Outputs from Frontiers in Pediatrics
#1,906
of 7,265 outputs
Outputs of similar age
#114,431
of 240,552 outputs
Outputs of similar age from Frontiers in Pediatrics
#11
of 35 outputs
Altmetric has tracked 24,620,113 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,265 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,552 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.