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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Comparison of Brain Development in Sow-Reared and Artificially Reared Piglets
|
|---|---|
| Published in |
Frontiers in Pediatrics, September 2016
|
| DOI | 10.3389/fped.2016.00095 |
| Pubmed ID | |
| Authors |
Reeba M. Jacob, Austin T. Mudd, Lindsey S. Alexander, Chron-Si Lai, Ryan N. Dilger |
| Abstract |
Provision of adequate nutrients is critical for proper growth and development of the neonate, yet the impact of breastfeeding versus formula feeding on neural maturation has to be fully determined. Using the piglet as a model for the human infant, our objective was to compare neurodevelopment of piglets that were either sow-reared (SR) or artificially reared (AR) in an artificial setting. Over a 25-day feeding study, piglets (1.5 ± 0.2 kg initial bodyweight) were either SR (n = 10) with ad libitum intake or AR (n = 29) receiving an infant formula modified to mimic the nutritional profile and intake pattern of sow's milk. At study conclusion, piglets were subjected to a standardized set of magnetic resonance imaging (MRI) procedures to quantify structure and composition of the brain. Diffusion tensor imaging, an MRI sequence that characterizes brain microstructure, revealed that SR piglets had greater (P < 0.05) average white matter (WM) (generated from a piglet specific brain atlas) fractional anisotropy (FA), and lower (P < 0.05) mean and radial and axial diffusivity values compared with AR piglets, suggesting differences in WM organization. Voxel-based morphometric analysis, a measure of white and gray matter (GM) volumes concentrations, revealed differences (P < 0.05) in bilateral development of GM clusters in the cortical brain regions of the AR piglets compared with SR piglets. Region of interest analysis revealed larger (P < 0.05) whole brain volumes in SR animals compared with AR, and certain subcortical regions to be larger (P < 0.05) as a percentage of whole brain volume in AR piglets compared with SR animals. Quantification of brain metabolites using magnetic resonance spectroscopy revealed SR piglets had higher (P < 0.05) concentrations of myo-inositol, glycerophosphocholine + phosphocholine, and creatine + phosphocreatine compared with AR piglets. However, glutamate + glutamine levels were higher (P < 0.05) in AR piglets when compared with SR animals. Overall, increases in brain metabolite concentrations, coupled with greater FA values in WM tracts and volume differences in GM of specific brain regions, suggest differences in myelin development and cell proliferation in SR versus AR piglets. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 47 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 30% |
| Researcher | 7 | 15% |
| Student > Master | 5 | 11% |
| Student > Bachelor | 4 | 9% |
| Other | 3 | 6% |
| Other | 7 | 15% |
| Unknown | 7 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 11 | 23% |
| Neuroscience | 4 | 9% |
| Nursing and Health Professions | 4 | 9% |
| Medicine and Dentistry | 4 | 9% |
| Psychology | 3 | 6% |
| Other | 6 | 13% |
| Unknown | 15 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 47. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2016.
All research outputs
#841,252
of 24,378,020 outputs
Outputs from Frontiers in Pediatrics
#127
of 7,095 outputs
Outputs of similar age
#16,123
of 327,696 outputs
Outputs of similar age from Frontiers in Pediatrics
#2
of 40 outputs
Altmetric has tracked 24,378,020 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,095 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,696 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.