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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pediatric Anti-N-Methyl-d-Aspartate Receptor Encephalitis: A Review with Pooled Analysis and Critical Care Emphasis
|
|---|---|
| Published in |
Frontiers in Pediatrics, November 2017
|
| DOI | 10.3389/fped.2017.00250 |
| Pubmed ID | |
| Authors |
Kenneth E. Remy, Jason W. Custer, Joshua Cappell, Cortney B. Foster, Nan A. Garber, L. Kyle Walker, Liliana Simon, Dayanand Bagdure |
| Abstract |
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is being recognized with increasing frequency among children. Given the paucity of evidence to guide the critical care management of these complex patients, we provide a comprehensive review of the literature with pooled analysis of published case reports and case series. We performed a comprehensive literature search using PubMed, Scopus, EMBASE, and Web of Science for relevant published studies. The literature search was conducted using the terms NMDA, anti-NMDA, Anti-N-methyl-d-aspartate, pediatric encephalitis, and anti-NMDAR and included articles published between 2005 and May 1, 2016. Forty-eight references met inclusion criteria accounting for 373 cases. For first-line treatments, 335 (89.8%) received high-dose corticosteroids, 296 received intravenous immunoglobulin (79.3%), and 116 (31%) received therapeutic plasma exchange. In these, 187 children (50.1%) had a full recovery with only minor deficits, 174 patients (46.7%) had partial recovery with major deficits, and 12 children died. In addition, 14 patients were reported to require mechanical ventilation. Anti-NMDA encephalitis is a formidable disease with great variation in clinical presentation and response to treatment. With early recognition of this second most common cause of pediatric encephalitis, a multidisciplinary approach by physicians may provide earlier access to first- and second-line therapies. Future studies are needed to examine the efficacy of these current therapeutic strategies on long-term morbidity. |
X Demographics
The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 10 | 32% |
| Canada | 3 | 10% |
| Switzerland | 2 | 6% |
| Uruguay | 1 | 3% |
| France | 1 | 3% |
| Turkey | 1 | 3% |
| United Kingdom | 1 | 3% |
| South Africa | 1 | 3% |
| Germany | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 8 | 26% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 21 | 68% |
| Scientists | 6 | 19% |
| Practitioners (doctors, other healthcare professionals) | 3 | 10% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 59 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 15% |
| Professor > Associate Professor | 7 | 12% |
| Other | 6 | 10% |
| Student > Ph. D. Student | 6 | 10% |
| Student > Postgraduate | 4 | 7% |
| Other | 6 | 10% |
| Unknown | 21 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 34% |
| Nursing and Health Professions | 3 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Neuroscience | 3 | 5% |
| Psychology | 3 | 5% |
| Other | 4 | 7% |
| Unknown | 23 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2019.
All research outputs
#2,102,859
of 25,918,104 outputs
Outputs from Frontiers in Pediatrics
#329
of 7,947 outputs
Outputs of similar age
#45,351
of 451,535 outputs
Outputs of similar age from Frontiers in Pediatrics
#3
of 65 outputs
Altmetric has tracked 25,918,104 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,947 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 451,535 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.