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The Genetic and Cellular Basis of Autosomal Dominant Polycystic Kidney Disease—A Primer for Clinicians

Overview of attention for article published in Frontiers in Pediatrics, December 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

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1 blog
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90 Mendeley
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Title
The Genetic and Cellular Basis of Autosomal Dominant Polycystic Kidney Disease—A Primer for Clinicians
Published in
Frontiers in Pediatrics, December 2017
DOI 10.3389/fped.2017.00279
Pubmed ID
Authors

Adrián Cordido, Lara Besada-Cerecedo, Miguel A. García-González

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders worldwide. In recent decades, the field has undergone a revolution, starting with the identification of causal ADPKD genes, including PKD1, PKD2, and the recently identified GANAB. In addition, advances defining the genetic mechanisms, protein localization and function, and the identification of numerous pathways involved in the disease process, have contributed to a better understanding of this illness. Together, this has led to a better prognosis, diagnosis, and treatment in clinical practice. In this mini review, we summarize and discuss new insights about the molecular mechanisms underlying ADPKD, including its genetics, protein function, and cellular pathways.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 90 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 11%
Student > Bachelor 9 10%
Researcher 8 9%
Student > Ph. D. Student 8 9%
Student > Postgraduate 4 4%
Other 17 19%
Unknown 34 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 21 23%
Medicine and Dentistry 17 19%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Agricultural and Biological Sciences 2 2%
Unspecified 2 2%
Other 11 12%
Unknown 34 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2018.
All research outputs
#2,624,501
of 23,012,811 outputs
Outputs from Frontiers in Pediatrics
#402
of 6,074 outputs
Outputs of similar age
#60,885
of 439,953 outputs
Outputs of similar age from Frontiers in Pediatrics
#10
of 77 outputs
Altmetric has tracked 23,012,811 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,074 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,953 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.