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Progression of Gastric Acid Production in Preterm Neonates: Utilization of In-vitro Method

Overview of attention for article published in Frontiers in Pediatrics, August 2018
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Title
Progression of Gastric Acid Production in Preterm Neonates: Utilization of In-vitro Method
Published in
Frontiers in Pediatrics, August 2018
DOI 10.3389/fped.2018.00211
Pubmed ID
Authors

Murali R. Palla, Shashidhar Harohalli, Tim N. Crawford, Nirmala Desai

Abstract

Background: Limited studies are done regarding ability to produce gastric acid in preterm infants and most studies used in vivo method of assessing gastric pH. Objectives: To assess the feasibility of using an in vitro method of measuring gastric pH in babies ≤ 28 weeks gestational age (GA) and determine whether changes in gastric pH differ with gestational age, mode of delivery, and use of antenatal steroids. Design/Methods: Prospective study that enrolled extremely low birth weight (ELBW) babies. Gastric aspirate collected before feeding. In vitro testing of gastric aspirates for pH were done on days of life 1, 3, 5, 7, 14, and 28 by using pH electrode. The pH was measured on each sample in triplicate, mean calculated and used for data analysis. Stastical methods included descriptive statistics, t-tests and repeated measures ANOVA. Results: 29 subjects ≤ 28 weeks or birth weight ≤ 1,000 g were enrolled. No significant change was noted in pH measurements over time. Antenatal steroids and mode of delivery did not affect gastric acid pH. Conclusion: The in vitro method for gastric pH measurements is non-invasive and affords more frequent testing. It would be useful in studying various conditions that may affect gastric pH.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 10%
Student > Bachelor 2 7%
Researcher 2 7%
Student > Master 2 7%
Student > Postgraduate 2 7%
Other 3 10%
Unknown 15 52%
Readers by discipline Count As %
Medicine and Dentistry 7 24%
Environmental Science 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Immunology and Microbiology 1 3%
Nursing and Health Professions 1 3%
Other 2 7%
Unknown 14 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2018.
All research outputs
#23,241,889
of 25,904,557 outputs
Outputs from Frontiers in Pediatrics
#5,225
of 7,980 outputs
Outputs of similar age
#300,026
of 342,566 outputs
Outputs of similar age from Frontiers in Pediatrics
#73
of 74 outputs
Altmetric has tracked 25,904,557 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,980 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,566 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.