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X Demographics
Mendeley readers
Attention Score in Context
| Title |
TRP Channels as Sensors and Signal Integrators of Redox Status Changes
|
|---|---|
| Published in |
Frontiers in Pharmacology, January 2011
|
| DOI | 10.3389/fphar.2011.00058 |
| Pubmed ID | |
| Authors |
Nobuaki Takahashi, Yasuo Mori |
| Abstract |
Proteins are capable of sensing the redox status of cells. Cysteine residues, which react with oxidants, reductants, and electrophiles, have been increasingly recognized as the mediators of this redox sensitivity. Cation channels encoded by the transient receptor potential (trp) gene superfamily are characterized by a wide variety of activation triggers that act from outside and inside the cell. Recent studies have revealed that a class of TRP channels is sensitive to changes in redox status and is notably susceptible to modifications of cysteine residues, such as oxidation, electrophilic reaction, and S-nitrosylation of sulfhydryls. In this review, we focus on TRP channels, which directly sense redox status, and discuss the biological significance of cysteine modifications and the consequences of this chemical reaction for physiological responses. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 107 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 22 | 20% |
| Student > Ph. D. Student | 20 | 19% |
| Student > Bachelor | 8 | 7% |
| Professor | 7 | 6% |
| Student > Master | 7 | 6% |
| Other | 19 | 18% |
| Unknown | 25 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 26 | 24% |
| Biochemistry, Genetics and Molecular Biology | 16 | 15% |
| Neuroscience | 12 | 11% |
| Medicine and Dentistry | 12 | 11% |
| Engineering | 4 | 4% |
| Other | 12 | 11% |
| Unknown | 26 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2017.
All research outputs
#18,313,878
of 22,675,759 outputs
Outputs from Frontiers in Pharmacology
#8,082
of 15,845 outputs
Outputs of similar age
#159,968
of 180,328 outputs
Outputs of similar age from Frontiers in Pharmacology
#33
of 44 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 15,845 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
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We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.