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Primary Phagocytosis of Neurons by Inflamed Microglia: Potential Roles in Neurodegeneration

Overview of attention for article published in Frontiers in Pharmacology, January 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

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1 X user
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1 Facebook page
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1 Wikipedia page

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170 Mendeley
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Title
Primary Phagocytosis of Neurons by Inflamed Microglia: Potential Roles in Neurodegeneration
Published in
Frontiers in Pharmacology, January 2012
DOI 10.3389/fphar.2012.00027
Pubmed ID
Authors

Jonas J. Neher, Urte Neniskyte, Guy C. Brown

Abstract

Microglial phagocytosis of dead or dying neurons can be beneficial by preventing the release of damaging and/or pro-inflammatory intracellular components. However, there is now evidence that under certain conditions, such as inflammation, microglia can also phagocytose viable neurons, thus executing their death. Such phagocytic cell death may result from exposure of phosphatidylserine (PS) or other eat-me signals on otherwise viable neurons as a result of physiological activation or sub-toxic insult, and neuronal phagocytosis by activated microglia. In this review, we discuss the mechanisms of phagocytic cell death and its potential roles in Alzheimer's Disease, Parkinson's Disease, and Frontotemporal Dementia.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 170 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Luxembourg 2 1%
United States 2 1%
Canada 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
Unknown 163 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 35 21%
Student > Ph. D. Student 32 19%
Student > Bachelor 27 16%
Student > Master 19 11%
Student > Doctoral Student 8 5%
Other 18 11%
Unknown 31 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 52 31%
Neuroscience 25 15%
Medicine and Dentistry 20 12%
Biochemistry, Genetics and Molecular Biology 18 11%
Pharmacology, Toxicology and Pharmaceutical Science 4 2%
Other 15 9%
Unknown 36 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2020.
All research outputs
#6,752,694
of 22,675,759 outputs
Outputs from Frontiers in Pharmacology
#2,701
of 15,845 outputs
Outputs of similar age
#62,696
of 244,088 outputs
Outputs of similar age from Frontiers in Pharmacology
#35
of 137 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 15,845 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,088 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.