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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Excitatory GABA: How a Correct Observation May Turn Out to be an Experimental Artifact
|
|---|---|
| Published in |
Frontiers in Pharmacology, January 2012
|
| DOI | 10.3389/fphar.2012.00065 |
| Pubmed ID | |
| Authors |
Piotr Bregestovski, Christophe Bernard |
| Abstract |
The concept of the excitatory action of GABA during early development is based on data obtained mainly in brain slice recordings. However, in vivo measurements as well as observations made in intact hippocampal preparations indicate that GABA is in fact inhibitory in rodents at early neonatal stages. The apparent excitatory action of GABA seems to stem from cellular injury due to the slicing procedure, which leads to accumulation of intracellular Cl(-) in injured neurons. This procedural artifact was shown to be attenuated through various manipulations such as addition of energy substrates more relevant to the in vivo situation. These observations question the very concept of excitatory GABA in immature neuronal networks. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| France | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 193 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 3% |
| Germany | 3 | 2% |
| France | 2 | 1% |
| Japan | 2 | 1% |
| Spain | 2 | 1% |
| Chile | 1 | <1% |
| Sweden | 1 | <1% |
| Finland | 1 | <1% |
| United Kingdom | 1 | <1% |
| Other | 5 | 3% |
| Unknown | 170 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 55 | 28% |
| Student > Ph. D. Student | 47 | 24% |
| Student > Master | 23 | 12% |
| Professor | 16 | 8% |
| Student > Bachelor | 10 | 5% |
| Other | 27 | 14% |
| Unknown | 15 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 82 | 42% |
| Neuroscience | 47 | 24% |
| Medicine and Dentistry | 18 | 9% |
| Engineering | 10 | 5% |
| Biochemistry, Genetics and Molecular Biology | 4 | 2% |
| Other | 9 | 5% |
| Unknown | 23 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2018.
All research outputs
#12,859,601
of 22,675,759 outputs
Outputs from Frontiers in Pharmacology
#3,536
of 15,845 outputs
Outputs of similar age
#142,892
of 244,088 outputs
Outputs of similar age from Frontiers in Pharmacology
#51
of 137 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 15,845 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,088 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.