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Mendeley readers
Attention Score in Context
| Title |
Pathological Alteration in the Choroid Plexus of Alzheimer’s Disease: Implication for New Therapy Approaches
|
|---|---|
| Published in |
Frontiers in Pharmacology, January 2012
|
| DOI | 10.3389/fphar.2012.00075 |
| Pubmed ID | |
| Authors |
Agnieszka Krzyzanowska, Eva Carro |
| Abstract |
Morphological alterations of choroid plexus in Alzheimer's disease (AD) have been extensively investigated. These changes include epithelial atrophy, thickening of the basement membrane, and stroma fibrosis. As a result, synthesis, secretory, and transportation functions are significantly altered resulting in decreased cerebrospinal fluid (CSF) turnover. Recent studies discuss the potential impacts of these changes, including the possibility of reduced resistance to stress insults and slow clearance of toxic compounds from CSF with specific reference to the amyloid peptide. Here, we review new evidences for AD-related changes in the choroid plexus. The data suggest that the significantly altered functions of the choroid plexus contribute to the multiparametric pathogenesis of late-onset AD. |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | 1% |
| Unknown | 75 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 20% |
| Researcher | 14 | 18% |
| Student > Master | 12 | 16% |
| Student > Bachelor | 8 | 11% |
| Student > Doctoral Student | 6 | 8% |
| Other | 13 | 17% |
| Unknown | 8 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 22% |
| Medicine and Dentistry | 15 | 20% |
| Neuroscience | 12 | 16% |
| Biochemistry, Genetics and Molecular Biology | 7 | 9% |
| Psychology | 3 | 4% |
| Other | 13 | 17% |
| Unknown | 9 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2015.
All research outputs
#1,921,518
of 22,664,644 outputs
Outputs from Frontiers in Pharmacology
#679
of 15,822 outputs
Outputs of similar age
#14,920
of 244,053 outputs
Outputs of similar age from Frontiers in Pharmacology
#11
of 137 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,822 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,053 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.