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Translational Concepts of mGluR5 in Synaptic Diseases of the Brain

Overview of attention for article published in Frontiers in Pharmacology, January 2012
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Title
Translational Concepts of mGluR5 in Synaptic Diseases of the Brain
Published in
Frontiers in Pharmacology, January 2012
DOI 10.3389/fphar.2012.00199
Pubmed ID
Authors

Thomas M. Piers, Dong Hyun Kim, Byeong C. Kim, Philip Regan, Daniel J. Whitcomb, Kwangwook Cho

Abstract

The G-protein coupled receptor family of glutamate receptors, termed metabotropic glutamate receptors (mGluRs), are implicated in numerous cellular mechanisms ranging from neural development to the processing of cognitive, sensory, and motor information. Over the last decade, multiple mGluR-related signal cascades have been identified at excitatory synapses, indicating their potential roles in various forms of synaptic function and dysfunction. This review highlights recent studies investigating mGluR5, a subtype of group I mGluRs, and its association with a number of developmental, psychiatric, and senile synaptic disorders with respect to associated synaptic proteins, with an emphasis on translational pre-clinical studies targeting mGluR5 in a range of synaptic diseases of the brain.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 3%
United Kingdom 1 <1%
Japan 1 <1%
Kazakhstan 1 <1%
Unknown 135 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 24%
Researcher 33 23%
Student > Master 18 13%
Student > Bachelor 13 9%
Student > Postgraduate 6 4%
Other 13 9%
Unknown 25 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 50 35%
Neuroscience 25 18%
Medicine and Dentistry 14 10%
Biochemistry, Genetics and Molecular Biology 12 8%
Pharmacology, Toxicology and Pharmaceutical Science 6 4%
Other 8 6%
Unknown 27 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 November 2012.
All research outputs
#17,671,894
of 22,687,320 outputs
Outputs from Frontiers in Pharmacology
#6,943
of 15,880 outputs
Outputs of similar age
#191,346
of 244,125 outputs
Outputs of similar age from Frontiers in Pharmacology
#79
of 137 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 15,880 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,125 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.