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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Free fatty acid receptors as therapeutic targets for the treatment of diabetes
|
|---|---|
| Published in |
Frontiers in Pharmacology, November 2014
|
| DOI | 10.3389/fphar.2014.00236 |
| Pubmed ID | |
| Authors |
Atsuhiko Ichimura, Sae Hasegawa, Mayu Kasubuchi, Ikuo Kimura |
| Abstract |
Nutrition regulates energy balance; however, dysfunction of energy balance can cause metabolic disorders, such as obesity and diabetes. Fatty acids are an essential energy source and signaling molecules that regulate various cellular processes and physiological functions. Recently, several orphan G protein-coupled receptors were identified as free fatty acid receptors (FFARs). GPR40/FFAR1 and GPR120/FFAR4 are activated by medium- and/or long-chain fatty acids, whereas GPR41/FFAR3 and GPR43/FFAR2 are activated by short-chain fatty acids. FFARs are regarded as targets for novel drugs to treat metabolic disorders, such as obesity and type 2 diabetes, because recent studies have showed that these receptors are involved in the energy metabolism in various tissues, including adipose, intestinal, and immune tissue. In this review, we summarize physiological roles of the FFARs, provide a comprehensive overview of energy regulation by FFARs, and discuss new prospects for treatment of metabolic disorders. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 206 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 203 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 18% |
| Researcher | 33 | 16% |
| Student > Bachelor | 27 | 13% |
| Student > Master | 22 | 11% |
| Other | 11 | 5% |
| Other | 30 | 15% |
| Unknown | 46 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 40 | 19% |
| Agricultural and Biological Sciences | 40 | 19% |
| Medicine and Dentistry | 23 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 17 | 8% |
| Immunology and Microbiology | 5 | 2% |
| Other | 24 | 12% |
| Unknown | 57 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2015.
All research outputs
#17,731,162
of 22,769,322 outputs
Outputs from Frontiers in Pharmacology
#7,023
of 16,009 outputs
Outputs of similar age
#177,194
of 262,797 outputs
Outputs of similar age from Frontiers in Pharmacology
#27
of 52 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,009 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,797 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.