Title |
Recent advances in circadian rhythms in cardiovascular system
|
---|---|
Published in |
Frontiers in Pharmacology, April 2015
|
DOI | 10.3389/fphar.2015.00071 |
Pubmed ID | |
Authors |
Lihong Chen, Guangrui Yang |
Abstract |
Growing evidence shows that intrinsic circadian clocks are tightly related to cardiovascular functions. The diurnal changes in blood pressure and heart rate are well known circadian rhythms. Endothelial function, platelet aggregation and thrombus formation exhibit circadian changes as well. The onset of many cardiovascular diseases (CVDs) or events, such as myocardial infarction, stroke, arrhythmia, and sudden cardiac death, also exhibits temporal trends. Furthermore, there is strong evidence from animal models and epidemiological studies showing that disruption of circadian rhythms is a significant risk factor for many CVDs, and the intervention of CVDs may have a time dependent effect. In this mini review, we summarized recent advances in our understanding of the relationship between circadian rhythm and cardiovascular physiology and diseases including blood pressure regulation and myocardial infarction. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 18 | 35% |
United States | 4 | 8% |
Switzerland | 2 | 4% |
Malaysia | 1 | 2% |
Unknown | 27 | 52% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 50 | 96% |
Practitioners (doctors, other healthcare professionals) | 2 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 178 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 26 | 15% |
Student > Bachelor | 25 | 14% |
Student > Ph. D. Student | 21 | 12% |
Researcher | 15 | 8% |
Student > Postgraduate | 11 | 6% |
Other | 32 | 18% |
Unknown | 48 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 37 | 21% |
Biochemistry, Genetics and Molecular Biology | 28 | 16% |
Agricultural and Biological Sciences | 15 | 8% |
Nursing and Health Professions | 9 | 5% |
Neuroscience | 7 | 4% |
Other | 27 | 15% |
Unknown | 55 | 31% |