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On the multiple roles of the voltage gated sodium channel β1 subunit in genetic diseases

Overview of attention for article published in Frontiers in Pharmacology, May 2015
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Title
On the multiple roles of the voltage gated sodium channel β1 subunit in genetic diseases
Published in
Frontiers in Pharmacology, May 2015
DOI 10.3389/fphar.2015.00108
Pubmed ID
Authors

Debora Baroni, Oscar Moran

Abstract

Voltage-gated sodium channels are intrinsic plasma membrane proteins that initiate the action potential in electrically excitable cells. They are composed of a pore-forming α-subunit and associated β-subunits. The β1-subunit was the first accessory subunit to be cloned. It can be important for controlling cell excitability and modulating multiple aspects of sodium channel physiology. Mutations of β1 are implicated in a wide variety of inherited pathologies, including epilepsy and cardiac conduction diseases. This review summarizes β1-subunit related channelopathies pointing out the current knowledge concerning their genetic background and their underlying molecular mechanisms.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Netherlands 1 1%
Unknown 74 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 13%
Student > Ph. D. Student 8 10%
Student > Bachelor 4 5%
Student > Doctoral Student 3 4%
Student > Master 3 4%
Other 6 8%
Unknown 43 56%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 14%
Biochemistry, Genetics and Molecular Biology 7 9%
Medicine and Dentistry 6 8%
Neuroscience 3 4%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 2 3%
Unknown 46 60%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2015.
All research outputs
#15,331,767
of 22,803,211 outputs
Outputs from Frontiers in Pharmacology
#6,396
of 16,018 outputs
Outputs of similar age
#156,185
of 265,520 outputs
Outputs of similar age from Frontiers in Pharmacology
#29
of 66 outputs
Altmetric has tracked 22,803,211 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,018 research outputs from this source. They receive a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,520 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.