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Cardiac cAMP: production, hydrolysis, modulation and detection

Overview of attention for article published in Frontiers in Pharmacology, October 2015
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Citations

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109 Mendeley
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Title
Cardiac cAMP: production, hydrolysis, modulation and detection
Published in
Frontiers in Pharmacology, October 2015
DOI 10.3389/fphar.2015.00203
Pubmed ID
Authors

Cédric Boularan, Céline Gales

Abstract

Cyclic adenosine 3',5'-monophosphate (cAMP) modulates a broad range of biological processes including the regulation of cardiac myocyte contractile function where it constitutes the main second messenger for β-adrenergic receptors' signaling to fulfill positive chronotropic, inotropic and lusitropic effects. A growing number of studies pinpoint the role of spatial organization of the cAMP signaling as an essential mechanism to regulate cAMP outcomes in cardiac physiology. Here, we will briefly discuss the complexity of cAMP synthesis and degradation in the cardiac context, describe the way to detect it and review the main pharmacological arsenal to modulate its availability.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 109 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 18%
Student > Bachelor 20 18%
Student > Master 15 14%
Researcher 10 9%
Student > Doctoral Student 8 7%
Other 12 11%
Unknown 24 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 30 28%
Agricultural and Biological Sciences 17 16%
Pharmacology, Toxicology and Pharmaceutical Science 12 11%
Medicine and Dentistry 12 11%
Engineering 4 4%
Other 9 8%
Unknown 25 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2015.
All research outputs
#15,348,067
of 22,829,683 outputs
Outputs from Frontiers in Pharmacology
#6,423
of 16,070 outputs
Outputs of similar age
#160,899
of 274,923 outputs
Outputs of similar age from Frontiers in Pharmacology
#48
of 104 outputs
Altmetric has tracked 22,829,683 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,070 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,923 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.