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Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment

Overview of attention for article published in Frontiers in Pharmacology, March 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

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6 X users

Readers on

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95 Mendeley
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Title
Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment
Published in
Frontiers in Pharmacology, March 2016
DOI 10.3389/fphar.2016.00078
Pubmed ID
Authors

Natacha Leroi, François Lallemand, Philippe Coucke, Agnès Noel, Philippe Martinive

Abstract

Radiotherapy (RT) is one of the most important modalities for cancer treatment. For many years, the impact of RT on cancer cells has been extensively studied. Recently, the tumor microenvironment (TME) emerged as one of the key factors in therapy resistance. RT is known to influence and modify diverse components of the TME. Hence, we intent to review data from the literature on the impact of low and high single dose, as well as fractionated RT on host cells (endothelial cells, fibroblasts, immune and inflammatory cells) and the extracellular matrix. Optimizing the schedule of RT (i.e., dose per fraction) and other treatment modalities is a current challenge. A better understanding of the cascade of events and TME remodeling following RT would be helpful to design optimal treatment combination.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 94 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 24%
Student > Master 19 20%
Researcher 10 11%
Student > Doctoral Student 7 7%
Student > Bachelor 7 7%
Other 13 14%
Unknown 16 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 18 19%
Agricultural and Biological Sciences 16 17%
Medicine and Dentistry 15 16%
Immunology and Microbiology 8 8%
Engineering 5 5%
Other 9 9%
Unknown 24 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 October 2016.
All research outputs
#13,112,875
of 22,858,915 outputs
Outputs from Frontiers in Pharmacology
#3,725
of 16,130 outputs
Outputs of similar age
#140,573
of 300,631 outputs
Outputs of similar age from Frontiers in Pharmacology
#33
of 94 outputs
Altmetric has tracked 22,858,915 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,130 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,631 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.