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Attention Score in Context
| Title |
Anti-Inflammatory Properties of Menthol and Menthone in Schistosoma mansoni Infection
|
|---|---|
| Published in |
Frontiers in Pharmacology, June 2016
|
| DOI | 10.3389/fphar.2016.00170 |
| Pubmed ID | |
| Authors |
Mauricio G. Zaia, Túlio di Orlando Cagnazzo, Karina A. Feitosa, Edson G. Soares, Lúcia H. Faccioli, Silmara M. Allegretti, Ana Afonso, Fernanda de Freitas Anibal |
| Abstract |
Schistosomiasis is a parasitic disease caused by several species of trematode worms and it is believed that more than 261 million people are affected worldwide. New drug development has become essential because there is a risk of the parasite becoming resistant to Praziquantel, the only drug available for this infection. This study evaluated parasitological, immunological and histological parameters in mice infected with Schistosoma mansoni and treated with an herbal commercial medicine. This drug consists of menthol (30-55%) and menthone (14-32%). A 60 day treatment regimen with the herbal medicine decreased the number of S. mansoni eggs in the feces, liver, and intestine and reduced the number of hepatic granulomas. We observed a reduction of 84% in blood eosinophilia and a decrease in the IL-4 and IL-10 blood levels after treatment. Therefore, we propose that schistosomiasis treatment with this herbal medicine for 60 days has an immunomodulatory and anti-inflammatory action in this animal model for schistosomiasis thus contributing to the decrease in physio pathological effects caused by S. mansoni infection. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 85 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 12% |
| Researcher | 9 | 10% |
| Student > Master | 8 | 9% |
| Student > Bachelor | 8 | 9% |
| Lecturer | 6 | 7% |
| Other | 16 | 19% |
| Unknown | 29 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 8 | 9% |
| Chemistry | 8 | 9% |
| Agricultural and Biological Sciences | 7 | 8% |
| Medicine and Dentistry | 7 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
| Other | 15 | 17% |
| Unknown | 36 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2019.
All research outputs
#17,808,979
of 22,877,793 outputs
Outputs from Frontiers in Pharmacology
#7,118
of 16,169 outputs
Outputs of similar age
#252,836
of 352,647 outputs
Outputs of similar age from Frontiers in Pharmacology
#53
of 116 outputs
Altmetric has tracked 22,877,793 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,169 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,647 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.