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X Demographics
Mendeley readers
Attention Score in Context
| Title |
CB2 and GPR55 Receptors as Therapeutic Targets for Systemic Immune Dysregulation
|
|---|---|
| Published in |
Frontiers in Pharmacology, August 2016
|
| DOI | 10.3389/fphar.2016.00264 |
| Pubmed ID | |
| Authors |
Juan Zhou, Ian Burkovskiy, Hyewon Yang, Joel Sardinha, Christian Lehmann |
| Abstract |
The endocannabinoid system (ECS) is involved in many physiological processes and has been suggested to play a critical role in the immune response and the central nervous system (CNS). Therefore, ECS modulation has potential therapeutic effects on immune dysfunctional disorders, such as sepsis and CNS injury-induced immunodeficiency syndrome (CIDS). In sepsis, excessive release of pro- and anti-inflammatory mediators results in multi-organ dysfunction, failure, and death. In CIDS, an acute CNS injury dysregulates a normally well-balanced interplay between CNS and the immune system, leading to increased patients' susceptibility to infections. In this review, we will discuss potential therapeutic modulation of the immune response in sepsis and CNS injury by manipulation of the ECS representing a novel target for immunotherapy. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 67% |
| Members of the public | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 2% |
| Unknown | 81 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 17% |
| Student > Bachelor | 13 | 16% |
| Student > Master | 11 | 13% |
| Student > Ph. D. Student | 10 | 12% |
| Other | 5 | 6% |
| Other | 9 | 11% |
| Unknown | 21 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 19% |
| Biochemistry, Genetics and Molecular Biology | 11 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 11% |
| Immunology and Microbiology | 5 | 6% |
| Agricultural and Biological Sciences | 5 | 6% |
| Other | 15 | 18% |
| Unknown | 22 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2016.
All research outputs
#15,433,648
of 24,558,777 outputs
Outputs from Frontiers in Pharmacology
#5,345
of 18,580 outputs
Outputs of similar age
#204,918
of 350,718 outputs
Outputs of similar age from Frontiers in Pharmacology
#54
of 153 outputs
Altmetric has tracked 24,558,777 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 18,580 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 350,718 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 153 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.