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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Current Therapeutic Cannabis Controversies and Clinical Trial Design Issues
|
|---|---|
| Published in |
Frontiers in Pharmacology, September 2016
|
| DOI | 10.3389/fphar.2016.00309 |
| Pubmed ID | |
| Authors |
Ethan B. Russo |
| Abstract |
This overview covers a wide range of cannabis topics, initially examining issues in dispensaries and self-administration, plus regulatory requirements for production of cannabis-based medicines, particularly the Food and Drug Administration "Botanical Guidance." The remainder pertains to various cannabis controversies that certainly require closer examination if the scientific, consumer, and governmental stakeholders are ever to reach consensus on safety issues, specifically: whether botanical cannabis displays herbal synergy of its components, pharmacokinetics of cannabis and dose titration, whether cannabis medicines produce cyclo-oxygenase inhibition, cannabis-drug interactions, and cytochrome P450 issues, whether cannabis randomized clinical trials are properly blinded, combatting the placebo effect in those trials via new approaches, the drug abuse liability (DAL) of cannabis-based medicines and their regulatory scheduling, their effects on cognitive function and psychiatric sequelae, immunological effects, cannabis and driving safety, youth usage, issues related to cannabis smoking and vaporization, cannabis concentrates and vape-pens, and laboratory analysis for contamination with bacteria and heavy metals. Finally, the issue of pesticide usage on cannabis crops is addressed. New and disturbing data on pesticide residues in legal cannabis products in Washington State are presented with the observation of an 84.6% contamination rate including potentially neurotoxic and carcinogenic agents. With ongoing developments in legalization of cannabis in medical and recreational settings, numerous scientific, safety, and public health issues remain. |
X Demographics
The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 10 | 40% |
| Switzerland | 2 | 8% |
| United Kingdom | 2 | 8% |
| Netherlands | 1 | 4% |
| Canada | 1 | 4% |
| Unknown | 9 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 68% |
| Practitioners (doctors, other healthcare professionals) | 5 | 20% |
| Scientists | 2 | 8% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 390 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 389 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 58 | 15% |
| Researcher | 54 | 14% |
| Student > Bachelor | 41 | 11% |
| Student > Ph. D. Student | 39 | 10% |
| Other | 29 | 7% |
| Other | 52 | 13% |
| Unknown | 117 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 54 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 38 | 10% |
| Biochemistry, Genetics and Molecular Biology | 29 | 7% |
| Agricultural and Biological Sciences | 25 | 6% |
| Chemistry | 22 | 6% |
| Other | 84 | 22% |
| Unknown | 138 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 106. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2023.
All research outputs
#380,377
of 24,667,989 outputs
Outputs from Frontiers in Pharmacology
#136
of 18,718 outputs
Outputs of similar age
#7,420
of 328,101 outputs
Outputs of similar age from Frontiers in Pharmacology
#6
of 167 outputs
Altmetric has tracked 24,667,989 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 18,718 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,101 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 167 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.