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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling
|
|---|---|
| Published in |
Frontiers in Pharmacology, March 2017
|
| DOI | 10.3389/fphar.2017.00153 |
| Pubmed ID | |
| Authors |
Wei Qin, Yongjiang Zheng, Bin-Zhi Qian, Meng Zhao |
| Abstract |
Prostate cancer is the most common cancer among men worldwide. However, current treatments for prostate cancer patients in advanced stage often fail because of relapse. Prostate cancer stem cells (PCSCs) are resistant to most standard therapies, and are considered to be a major mechanism of cancer metastasis and recurrence. In this review, we summarized current understanding of PCSCs and their self-renewal signaling pathways with a specific focus on Wnt signaling. Although multiple Wnt inhibitors have been developed to target PCSCs, their application is still limited by inefficient delivery and toxicity in vivo. Recently, nanotechnology has opened a new avenue for cancer drug delivery, which significantly increases specificity and reduces toxicity. These nanotechnology-based drug delivery methods showed great potential in targeting PCSCs. Here, we summarized current advancement of nanotechnology-based therapeutic strategies for targeting PCSCs and highlighted the challenges and perspectives in designing future therapies to eliminate PCSCs. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 13% |
| Colombia | 1 | 13% |
| Mexico | 1 | 13% |
| Switzerland | 1 | 13% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 88% |
| Science communicators (journalists, bloggers, editors) | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 68 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 18% |
| Student > Master | 11 | 16% |
| Researcher | 6 | 9% |
| Student > Bachelor | 6 | 9% |
| Professor > Associate Professor | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 23 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 11 | 16% |
| Medicine and Dentistry | 10 | 15% |
| Agricultural and Biological Sciences | 7 | 10% |
| Chemistry | 3 | 4% |
| Immunology and Microbiology | 2 | 3% |
| Other | 11 | 16% |
| Unknown | 24 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2021.
All research outputs
#6,505,767
of 23,316,003 outputs
Outputs from Frontiers in Pharmacology
#2,749
of 16,764 outputs
Outputs of similar age
#103,846
of 309,299 outputs
Outputs of similar age from Frontiers in Pharmacology
#40
of 201 outputs
Altmetric has tracked 23,316,003 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 16,764 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,299 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 201 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.