Title |
An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol
|
---|---|
Published in |
Frontiers in Pharmacology, June 2017
|
DOI | 10.3389/fphar.2017.00422 |
Pubmed ID | |
Authors |
Paula Morales, Patricia H. Reggio, Nadine Jagerovic |
Abstract |
Cannabidiol (CBD) has been traditionally used in Cannabis-based preparation, however historically, it has received far less interest as a single drug than the other components of Cannabis. Currently, CBD generates considerable interest due to its beneficial neuroprotective, antiepileptic, anxiolytic, antipsychotic, and anti-inflammatory properties. Therefore, the CBD scaffold becomes of increasing interest for medicinal chemists. This review provides an overview of the chemical structure of natural and synthetic CBD derivatives including the molecular targets associated with these compounds. A clear identification of their biological targets has been shown to be still very challenging. |
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Country | Count | As % |
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Spain | 3 | 21% |
United States | 2 | 14% |
Argentina | 1 | 7% |
Switzerland | 1 | 7% |
Unknown | 7 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 13 | 93% |
Scientists | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 381 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 61 | 16% |
Student > Ph. D. Student | 53 | 14% |
Researcher | 48 | 13% |
Student > Master | 32 | 8% |
Other | 22 | 6% |
Other | 50 | 13% |
Unknown | 115 | 30% |
Readers by discipline | Count | As % |
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Chemistry | 61 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 42 | 11% |
Agricultural and Biological Sciences | 31 | 8% |
Medicine and Dentistry | 30 | 8% |
Biochemistry, Genetics and Molecular Biology | 30 | 8% |
Other | 61 | 16% |
Unknown | 126 | 33% |