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International Clinical Trials in Latin American and Caribbean Countries: Research and Development to Meet Local Health Needs

Overview of attention for article published in Frontiers in Pharmacology, January 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

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14 X users

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Title
International Clinical Trials in Latin American and Caribbean Countries: Research and Development to Meet Local Health Needs
Published in
Frontiers in Pharmacology, January 2018
DOI 10.3389/fphar.2017.00961
Pubmed ID
Authors

Ricardo E. da Silva, Angélica A. Amato, Dirce B. Guilhem, Marta R. de Carvalho, Maria R. C. G. Novaes

Abstract

Introduction: Although international health research involves some benefits for the host countries, such as access to innovative treatments, the research itself may not be aligned with their communities' actual health needs. Objective: To map the global landscape of clinical trials run in Latin American and Caribbean countries and discuss the addressing of local health needs in the agenda of international clinical trials. Methods: The present study is a cross-sectional overview and used data referent to studies registered between 01/01/2014 and 12/31/2014 in the World Health Organization's (WHO) International Clinical Trials Registry Platform (ICTRP). Results: Non-communicable diseases such as diabetes, cancer, and asthma-studies which were financed mainly by industries-were the conditions investigated most in the region of Latin America and the Caribbean. The neglected diseases, on the other hand, such as Chagas disease, and dengue, made up 1% of the total number of studies. Hospitals and nonprofit nongovernmental organizations prioritize resources for investigating new drugs for neglected diseases, such as Chagas disease and dengue. Conclusion: The international multicenter clinical trials for investigating new drugs are aligned with the health needs of the region of Latin America and the Caribbean, when one considers the burden resulting from the non-communicable diseases in this region. However, the transmissible diseases, such as tuberculosis and AIDS, and the neglected diseases, such as Chagas disease and dengue, which have an important impact on public health in this region, continue to arouse little interest among the institutions which finance the clinical trials.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 22%
Student > Bachelor 7 11%
Researcher 6 9%
Student > Doctoral Student 4 6%
Other 4 6%
Other 12 19%
Unknown 17 27%
Readers by discipline Count As %
Medicine and Dentistry 17 27%
Biochemistry, Genetics and Molecular Biology 3 5%
Nursing and Health Professions 3 5%
Agricultural and Biological Sciences 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Other 14 22%
Unknown 21 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2018.
All research outputs
#3,932,284
of 24,598,501 outputs
Outputs from Frontiers in Pharmacology
#1,889
of 18,628 outputs
Outputs of similar age
#80,711
of 452,025 outputs
Outputs of similar age from Frontiers in Pharmacology
#27
of 265 outputs
Altmetric has tracked 24,598,501 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 18,628 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 452,025 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 265 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.