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Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review

Overview of attention for article published in Frontiers in Pharmacology, March 2018
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Title
Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review
Published in
Frontiers in Pharmacology, March 2018
DOI 10.3389/fphar.2018.00188
Pubmed ID
Authors

Ming Peng, Ya X. Yi, Tong Zhang, Yue Ding, Jian Le

Abstract

Panax notoginseng (Sanqi), a traditional Chinese medical drug which has been applied to medical use for over four centuries, contains high content of dammarane-type tetracyclic triterpenoid saponins. A number of stereoisomeric dammarane-type saponins exist in this precious herb, and some are particularly regarded as "biomarkers" in processed notoginseng. Contemporary researches have indicated that some saponin stereoisomers may show stereospecific pharmacological activities, such as anti-tumor, antioxidative, anti-photoaging, anti-inflammatory, antidiabetic, and neuro-protective activities, as well as stereoselective effects on ion channel current regulation, cardiovascular system, and immune system. The current review provides a comprehensive overview of chemical compositions of raw and processed P. notoginseng with a particular emphasis on saponin stereoisomers. Besides, the pharmacological and pharmacokinetic researches, as well as determination and biotechnological preparation methods of stereoisomeric saponins in notoginseng are discussed extensively.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 23%
Researcher 4 11%
Student > Postgraduate 4 11%
Student > Master 2 6%
Student > Bachelor 1 3%
Other 4 11%
Unknown 12 34%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 4 11%
Agricultural and Biological Sciences 4 11%
Medicine and Dentistry 3 9%
Biochemistry, Genetics and Molecular Biology 2 6%
Linguistics 1 3%
Other 5 14%
Unknown 16 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2018.
All research outputs
#20,468,008
of 23,026,672 outputs
Outputs from Frontiers in Pharmacology
#10,242
of 16,337 outputs
Outputs of similar age
#294,725
of 333,594 outputs
Outputs of similar age from Frontiers in Pharmacology
#239
of 378 outputs
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So far Altmetric has tracked 16,337 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 378 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.