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Anti-gout Potential of Malaysian Medicinal Plants

Overview of attention for article published in Frontiers in Pharmacology, March 2018
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Title
Anti-gout Potential of Malaysian Medicinal Plants
Published in
Frontiers in Pharmacology, March 2018
DOI 10.3389/fphar.2018.00261
Pubmed ID
Authors

Fazleen I. Abu Bakar, Mohd F. Abu Bakar, Asmah Rahmat, Norazlin Abdullah, Siti F. Sabran, Susi Endrini

Abstract

Gout is a type of arthritis that causes painful inflammation in one or more joints. In gout, elevation of uric acid in the blood triggers the formation of crystals, causing joint pain. Malaysia is a mega-biodiversity country that is rich in medicinal plants species. Therefore, its flora might offer promising therapies for gout. This article aims to systematically review the anti-gout potential of Malaysian medicinal plants. Articles on gout published from 2000 to 2017 were identified using PubMed, Scopus, ScienceDirect, and Google Scholar with the following keyword search terms: "gout," "medicinal plants," "Malaysia," "epidemiology," "in vitro," and "in vivo." In this study, 85 plants were identified as possessing anti-gout activity. These plants had higher percentages of xanthine oxidase inhibitory activity (>85%); specifically, the Momordica charantia, Chrysanthemum indicum, Cinnamomum cassia, Kaempferia galanga, Artemisia vulgaris, and Morinda elliptica had the highest values, due to their diverse natural bioactive compounds, which include flavonoids, phenolics, tannin, coumarins, luteolin, and apigenin. This review summarizes the anti-gout potential of Malaysian medicinal plants but the mechanisms, active compounds, pharmacokinetics, bioavailability, and safety of the plants still remain to be elucidated.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 185 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 32 17%
Lecturer 20 11%
Student > Master 15 8%
Student > Ph. D. Student 9 5%
Unspecified 9 5%
Other 26 14%
Unknown 74 40%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 30 16%
Medicine and Dentistry 17 9%
Biochemistry, Genetics and Molecular Biology 13 7%
Agricultural and Biological Sciences 11 6%
Chemistry 11 6%
Other 27 15%
Unknown 76 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2018.
All research outputs
#14,970,944
of 23,028,364 outputs
Outputs from Frontiers in Pharmacology
#5,297
of 16,343 outputs
Outputs of similar age
#200,435
of 331,443 outputs
Outputs of similar age from Frontiers in Pharmacology
#128
of 378 outputs
Altmetric has tracked 23,028,364 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,343 research outputs from this source. They receive a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,443 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 378 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.