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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Biologically Targeted Magnetic Hyperthermia: Potential and Limitations
|
|---|---|
| Published in |
Frontiers in Pharmacology, August 2018
|
| DOI | 10.3389/fphar.2018.00831 |
| Pubmed ID | |
| Authors |
David Chang, May Lim, Jeroen A. C. M. Goos, Ruirui Qiao, Yun Yee Ng, Friederike M. Mansfeld, Michael Jackson, Thomas P. Davis, Maria Kavallaris |
| Abstract |
Hyperthermia, the mild elevation of temperature to 40-43°C, can induce cancer cell death and enhance the effects of radiotherapy and chemotherapy. However, achievement of its full potential as a clinically relevant treatment modality has been restricted by its inability to effectively and preferentially heat malignant cells. The limited spatial resolution may be circumvented by the intravenous administration of cancer-targeting magnetic nanoparticles that accumulate in the tumor, followed by the application of an alternating magnetic field to raise the temperature of the nanoparticles located in the tumor tissue. This targeted approach enables preferential heating of malignant cancer cells whilst sparing the surrounding normal tissue, potentially improving the effectiveness and safety of hyperthermia. Despite promising results in preclinical studies, there are numerous challenges that must be addressed before this technique can progress to the clinic. This review discusses these challenges and highlights the current understanding of targeted magnetic hyperthermia. |
X Demographics
The data shown below were collected from the profiles of 40 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 3 | 8% |
| Chile | 3 | 8% |
| India | 2 | 5% |
| United States | 2 | 5% |
| Switzerland | 2 | 5% |
| United Kingdom | 2 | 5% |
| Indonesia | 2 | 5% |
| Netherlands | 1 | 3% |
| Lebanon | 1 | 3% |
| Other | 7 | 18% |
| Unknown | 15 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 27 | 68% |
| Scientists | 10 | 25% |
| Practitioners (doctors, other healthcare professionals) | 2 | 5% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 591 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 591 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 104 | 18% |
| Student > Master | 91 | 15% |
| Student > Bachelor | 65 | 11% |
| Researcher | 62 | 10% |
| Student > Doctoral Student | 23 | 4% |
| Other | 61 | 10% |
| Unknown | 185 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 66 | 11% |
| Engineering | 62 | 10% |
| Materials Science | 54 | 9% |
| Biochemistry, Genetics and Molecular Biology | 51 | 9% |
| Physics and Astronomy | 34 | 6% |
| Other | 98 | 17% |
| Unknown | 226 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2020.
All research outputs
#1,264,579
of 25,158,951 outputs
Outputs from Frontiers in Pharmacology
#466
of 19,317 outputs
Outputs of similar age
#26,435
of 336,963 outputs
Outputs of similar age from Frontiers in Pharmacology
#13
of 384 outputs
Altmetric has tracked 25,158,951 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 19,317 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,963 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 384 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.