Title |
Is There a Relationship between DNA Methylation and Phenotypic Plasticity in Invertebrates?
|
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Published in |
Frontiers in Physiology, January 2012
|
DOI | 10.3389/fphys.2011.00116 |
Pubmed ID | |
Authors |
Steven B. Roberts, Mackenzie R. Gavery |
Abstract |
There is a significant amount of variation in DNA methylation characteristics across organisms. Likewise, the biological role of DNA methylation varies across taxonomic lineages. The complexity of DNA methylation patterns in invertebrates has only recently begun to be characterized in-depth. In some invertebrate species that have been examined to date, methylated DNA is found primarily within coding regions and patterning is closely associated with gene function. Here we provide a perspective on the potential role of DNA methylation in these invertebrates with a focus on how limited methylation may contribute to increased phenotypic plasticity in highly fluctuating environments. Specifically, limited methylation could facilitate a variety of transcriptional opportunities including access to alternative transcription start sites, increasing sequence mutations, exon skipping, and transient methylation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Switzerland | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 50% |
Members of the public | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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France | 4 | 2% |
United States | 4 | 2% |
Germany | 1 | <1% |
New Caledonia | 1 | <1% |
Czechia | 1 | <1% |
Finland | 1 | <1% |
Spain | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 202 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 45 | 21% |
Researcher | 39 | 18% |
Student > Master | 39 | 18% |
Student > Bachelor | 27 | 13% |
Student > Doctoral Student | 15 | 7% |
Other | 26 | 12% |
Unknown | 25 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 121 | 56% |
Biochemistry, Genetics and Molecular Biology | 35 | 16% |
Environmental Science | 13 | 6% |
Earth and Planetary Sciences | 3 | 1% |
Immunology and Microbiology | 2 | <1% |
Other | 12 | 6% |
Unknown | 30 | 14% |