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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of Exosomes/Microvesicles in the Nervous System and Use in Emerging Therapies
|
|---|---|
| Published in |
Frontiers in Physiology, January 2012
|
| DOI | 10.3389/fphys.2012.00228 |
| Pubmed ID | |
| Authors |
Charles Pin-Kuang Lai, Xandra Owen Breakefield |
| Abstract |
Extracellular membrane vesicles (EMVs) are nanometer sized vesicles, including exosomes and microvesicles capable of transferring DNAs, mRNAs, microRNAs, non-coding RNAs, proteins, and lipids among cells without direct cell-to-cell contact, thereby representing a novel form of intercellular communication. Many cells in the nervous system have been shown to release EMVs, implicating their active roles in development, function, and pathologies of this system. While substantial progress has been made in understanding the biogenesis, biophysical properties, and involvement of EMVs in diseases, relatively less information is known about their biological function in the normal nervous system. In addition, since EMVs are endogenous vehicles with low immunogenicity, they have also been actively investigated for the delivery of therapeutic genes/molecules in treatment of cancer and neurological diseases. The present review summarizes current knowledge about EMV functions in the nervous system under both physiological and pathological conditions, as well as emerging EMV-based therapies that could be applied to the nervous system in the foreseeable future. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 329 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 4 | 1% |
| United States | 3 | <1% |
| Germany | 1 | <1% |
| Chile | 1 | <1% |
| Unknown | 320 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 69 | 21% |
| Researcher | 68 | 21% |
| Student > Bachelor | 36 | 11% |
| Student > Master | 32 | 10% |
| Student > Doctoral Student | 16 | 5% |
| Other | 55 | 17% |
| Unknown | 53 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 96 | 29% |
| Biochemistry, Genetics and Molecular Biology | 46 | 14% |
| Medicine and Dentistry | 36 | 11% |
| Neuroscience | 32 | 10% |
| Engineering | 11 | 3% |
| Other | 40 | 12% |
| Unknown | 68 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2013.
All research outputs
#6,750,904
of 22,669,724 outputs
Outputs from Frontiers in Physiology
#3,169
of 13,462 outputs
Outputs of similar age
#62,693
of 244,072 outputs
Outputs of similar age from Frontiers in Physiology
#67
of 309 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 13,462 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,072 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 309 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.