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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Contribution of oxidative stress to endothelial dysfunction in hypertension
|
|---|---|
| Published in |
Frontiers in Physiology, January 2012
|
| DOI | 10.3389/fphys.2012.00441 |
| Pubmed ID | |
| Authors |
Bruno R. Silva, Laena Pernomian, Lusiane M. Bendhack |
| Abstract |
Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In the cardiovascular system reactive oxygen species play a pivotal role in controlling the endothelial function and vascular tone. Physiologically, the endothelium-derived relaxing factors (EDRFs) and endothelium-derived contractile factors (EDCFs) that have functions on the vascular smooth muscle cells. The relaxation induced by the EDRFs nitric oxide (NO), prostacyclin, and the endothelium-derived hyperpolarization factor (EDHF) could be impaired in hypertension. The impaired ability of endothelial cells to release NO along with enhanced EDCFs production has been described to contribute to the endothelium dysfunction, which appears to lead to several cardiovascular diseases. The present review discusses the role of oxidative stress, vascular endothelium, and vascular tone control by EDRFs, mainly NO, and EDCFs in different models of experimental hypertension. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| Colombia | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 107 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 18% |
| Student > Bachelor | 19 | 17% |
| Student > Master | 12 | 11% |
| Researcher | 9 | 8% |
| Student > Doctoral Student | 5 | 5% |
| Other | 20 | 18% |
| Unknown | 25 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 25% |
| Biochemistry, Genetics and Molecular Biology | 17 | 15% |
| Medicine and Dentistry | 17 | 15% |
| Nursing and Health Professions | 6 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Other | 14 | 13% |
| Unknown | 24 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2020.
All research outputs
#15,256,901
of 22,687,320 outputs
Outputs from Frontiers in Physiology
#6,592
of 13,480 outputs
Outputs of similar age
#163,212
of 244,125 outputs
Outputs of similar age from Frontiers in Physiology
#154
of 309 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,480 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,125 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 309 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.