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An emerging role for microRNA in the regulation of endothelin-1

Overview of attention for article published in Frontiers in Physiology, January 2013
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  • Good Attention Score compared to outputs of the same age and source (65th percentile)

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Title
An emerging role for microRNA in the regulation of endothelin-1
Published in
Frontiers in Physiology, January 2013
DOI 10.3389/fphys.2013.00022
Pubmed ID
Authors

Mollie E. Jacobs, Charles S. Wingo, Brian D. Cain

Abstract

Endothelin-1 (ET-1) is a peptide signaling molecule serving diverse functions in many different tissues such as the vasculature and the kidney. The primary mechanism thought to control ET-1 bioavailability is the rate of transcription from the ET-1 gene (EDN1), but recent research suggests that EDN1 expression is attenuated by microRNA (miRNA)-mediated regulation. The action of specific miRNAs on EDN1 mRNA appears to vary greatly in a tissue specific manner. This review provides a summary of our current understanding of miRNA-EDN1 interaction.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 18%
Researcher 5 15%
Student > Master 5 15%
Student > Postgraduate 3 9%
Student > Bachelor 2 6%
Other 6 18%
Unknown 7 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 32%
Agricultural and Biological Sciences 8 24%
Medicine and Dentistry 3 9%
Sports and Recreations 1 3%
Immunology and Microbiology 1 3%
Other 2 6%
Unknown 8 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2013.
All research outputs
#13,676,457
of 22,696,971 outputs
Outputs from Frontiers in Physiology
#4,792
of 13,504 outputs
Outputs of similar age
#161,854
of 280,682 outputs
Outputs of similar age from Frontiers in Physiology
#137
of 398 outputs
Altmetric has tracked 22,696,971 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,504 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,682 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 398 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.