Title |
Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer
|
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Published in |
Frontiers in Physiology, January 2014
|
DOI | 10.3389/fphys.2014.00002 |
Pubmed ID | |
Authors |
Joshua McCarroll, Joann Teo, Cyrille Boyer, David Goldstein, Maria Kavallaris, Phoebe A. Phillips |
Abstract |
Despite improvements in our understanding of pancreatic cancer and the emerging concept of personalized medicine for the treatment of this disease, it is still the fourth most common cause of cancer death in the western world. It is established that pancreatic cancer is a highly heterogeneous disease with a complex tumor microenvironment. Indeed the extensive stroma surrounding the cancer cells has been shown to be important in promoting tumor growth and metastases, as well as sequestering chemotherapeutic agents consequently decreasing delivery to the tumor cells. Nanotechnology has come to the forefront in the areas of medical diagnostics, imaging, and therapeutic drug delivery. This review will focus on the potential applications of nanotechnology for diagnosis, imaging, and delivery of therapeutic agents for the treatment of pancreatic cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | <1% |
Netherlands | 1 | <1% |
France | 1 | <1% |
Egypt | 1 | <1% |
Unknown | 106 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 23 | 21% |
Student > Master | 17 | 15% |
Student > Bachelor | 16 | 15% |
Researcher | 16 | 15% |
Other | 6 | 5% |
Other | 14 | 13% |
Unknown | 18 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 19% |
Agricultural and Biological Sciences | 18 | 16% |
Biochemistry, Genetics and Molecular Biology | 16 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 12 | 11% |
Chemistry | 10 | 9% |
Other | 14 | 13% |
Unknown | 19 | 17% |