Title |
Mega roles of microRNAs in regulation of skeletal muscle health and disease
|
---|---|
Published in |
Frontiers in Physiology, January 2014
|
DOI | 10.3389/fphys.2014.00239 |
Pubmed ID | |
Authors |
Mridula Sharma, Prasanna Kumar Juvvuna, Himani Kukreti, Craig McFarlane |
Abstract |
Skeletal muscle is a dynamic tissue with remarkable plasticity. Skeletal muscle growth and regeneration are highly organized processes thus it is not surprising that a high degree of complexity exists in the regulation of these processes. Recent discovery of non-coding microRNAs (miRNAs) has prompted extensive research in understanding the roles of these molecules in skeletal muscle. Research so far shows that miRNAs play a very significant role at every aspect of muscle biology. Besides muscle growth, development, and regeneration miRNAs are also involved in the pathology of muscle diseases and metabolism. In this review, recent advancements in miRNA function during myogenesis, exercise, atrophy, aging, and dystrophy are discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 3 | 43% |
Norway | 1 | 14% |
Switzerland | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 2 | 1% |
United States | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 134 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 27 | 20% |
Researcher | 25 | 18% |
Student > Master | 16 | 12% |
Student > Postgraduate | 12 | 9% |
Student > Bachelor | 11 | 8% |
Other | 23 | 17% |
Unknown | 24 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 38 | 28% |
Biochemistry, Genetics and Molecular Biology | 32 | 23% |
Medicine and Dentistry | 12 | 9% |
Sports and Recreations | 10 | 7% |
Nursing and Health Professions | 4 | 3% |
Other | 13 | 9% |
Unknown | 29 | 21% |