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Adventitial inflammation and its interaction with intimal atherosclerotic lesions

Overview of attention for article published in Frontiers in Physiology, August 2014
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Title
Adventitial inflammation and its interaction with intimal atherosclerotic lesions
Published in
Frontiers in Physiology, August 2014
DOI 10.3389/fphys.2014.00296
Pubmed ID
Authors

Mohammadreza Akhavanpoor, Susanne Wangler, Christian A. Gleissner, Grigorios Korosoglou, Hugo A. Katus, Christian Erbel

Abstract

The presence of adventitial inflammation in correlation with atherosclerotic lesions has been recognized for decades. In the last years, several studies have investigated the relevance and impact of adventitial inflammation on atherogenesis. In the abdominal aorta of elderly Apoe(-/-) mice, adventitial inflammatory structures were characterized as organized ectopic lymphoid tissue, and therefore termed adventitial tertiary lymphoid organs (ATLOs). These ATLOs possess similarities in development, structure and function to secondary lymphoid organs. A crosstalk between intimal atherosclerotic lesions and ATLOs has been suggested, and several studies could demonstrate a potential role for medial vascular smooth muscle cells in this process. We here review the development, phenotypic characteristics, and function of ATLOs in atherosclerosis. Furthermore, we discuss the possible role of medial vascular smooth muscle cells and their interaction between plaque and ATLOs.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 23%
Researcher 6 15%
Student > Bachelor 4 10%
Student > Postgraduate 3 8%
Student > Master 3 8%
Other 4 10%
Unknown 10 26%
Readers by discipline Count As %
Medicine and Dentistry 13 33%
Agricultural and Biological Sciences 6 15%
Biochemistry, Genetics and Molecular Biology 3 8%
Chemistry 2 5%
Arts and Humanities 1 3%
Other 3 8%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2014.
All research outputs
#20,233,547
of 22,759,618 outputs
Outputs from Frontiers in Physiology
#9,330
of 13,560 outputs
Outputs of similar age
#193,891
of 230,503 outputs
Outputs of similar age from Frontiers in Physiology
#82
of 122 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,560 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.