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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Hypertrophic cardiomyopathy: a heart in need of an energy bar?
|
|---|---|
| Published in |
Frontiers in Physiology, August 2014
|
| DOI | 10.3389/fphys.2014.00309 |
| Pubmed ID | |
| Authors |
Styliani Vakrou, M. Roselle Abraham |
| Abstract |
Hypertrophic cardiomyopathy (HCM) has been recently recognized as the most common inherited cardiovascular disorder, affecting 1 in 500 adults worldwide. HCM is characterized by myocyte hypertrophy resulting in thickening of the ventricular wall, myocyte disarray, interstitial and/or replacement fibrosis, decreased ventricular cavity volume and diastolic dysfunction. HCM is also the most common cause of sudden death in the young. A large proportion of patients diagnosed with HCM have mutations in sarcomeric proteins. However, it is unclear how these mutations lead to the cardiac phenotype, which is variable even in patients carrying the same causal mutation. Abnormalities in calcium cycling, oxidative stress, mitochondrial dysfunction and energetic deficiency have been described constituting the basis of therapies in experimental models of HCM and HCM patients. This review focuses on evidence supporting the role of cellular metabolism and mitochondria in HCM. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 122 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 19% |
| Student > Ph. D. Student | 21 | 17% |
| Student > Bachelor | 14 | 11% |
| Student > Master | 12 | 10% |
| Other | 10 | 8% |
| Other | 26 | 21% |
| Unknown | 18 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 35% |
| Biochemistry, Genetics and Molecular Biology | 31 | 25% |
| Agricultural and Biological Sciences | 14 | 11% |
| Business, Management and Accounting | 3 | 2% |
| Engineering | 3 | 2% |
| Other | 9 | 7% |
| Unknown | 21 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2014.
All research outputs
#14,783,695
of 22,760,687 outputs
Outputs from Frontiers in Physiology
#5,653
of 13,560 outputs
Outputs of similar age
#129,344
of 235,512 outputs
Outputs of similar age from Frontiers in Physiology
#46
of 118 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,560 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,512 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.