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BK channel activators and their therapeutic perspectives

Overview of attention for article published in Frontiers in Physiology, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

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2 X users
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2 patents
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1 Wikipedia page

Readers on

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166 Mendeley
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Title
BK channel activators and their therapeutic perspectives
Published in
Frontiers in Physiology, October 2014
DOI 10.3389/fphys.2014.00389
Pubmed ID
Authors

Bo H. Bentzen, Søren-Peter Olesen, Lars C. B. Rønn, Morten Grunnet

Abstract

The large conductance calcium- and voltage-activated K(+) channel (KCa1.1, BK, MaxiK) is ubiquitously expressed in the body, and holds the ability to integrate changes in intracellular calcium and membrane potential. This makes the BK channel an important negative feedback system linking increases in intracellular calcium to outward hyperpolarizing potassium currents. Consequently, the channel has many important physiological roles including regulation of smooth muscle tone, neurotransmitter release and neuronal excitability. Additionally, cardioprotective roles have been revealed in recent years. After a short introduction to the structure, function and regulation of BK channels, we review the small organic molecules activating BK channels and how these tool compounds have helped delineate the roles of BK channels in health and disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 <1%
India 1 <1%
Canada 1 <1%
United States 1 <1%
Poland 1 <1%
Unknown 161 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 22%
Researcher 22 13%
Student > Bachelor 20 12%
Student > Master 20 12%
Professor > Associate Professor 8 5%
Other 24 14%
Unknown 36 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 33 20%
Biochemistry, Genetics and Molecular Biology 25 15%
Neuroscience 22 13%
Medicine and Dentistry 19 11%
Pharmacology, Toxicology and Pharmaceutical Science 15 9%
Other 15 9%
Unknown 37 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2020.
All research outputs
#4,441,743
of 22,765,347 outputs
Outputs from Frontiers in Physiology
#2,193
of 13,560 outputs
Outputs of similar age
#50,386
of 255,208 outputs
Outputs of similar age from Frontiers in Physiology
#7
of 125 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,560 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,208 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.