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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells
|
|---|---|
| Published in |
Frontiers in Physiology, January 2015
|
| DOI | 10.3389/fphys.2015.00001 |
| Pubmed ID | |
| Authors |
Zhenzhen Liu, Paul A. Roche |
| Abstract |
Dendritic cells (DCs) are outstanding antigen presenting cells (APCs) due to their robust ability to internalize extracellular antigens using endocytic processes such as receptor-mediated endocytosis, phagocytosis, and macropinocytosis. Macropinocytosis mediates the non-specific uptake of soluble antigens and occurs in DCs constitutively. Macropinocytosis plays a key role in DC-mediated antigen presentation to T cells against pathogens and the efficiency of macropinocytosis in antigen capture is regulated during the process of DC maturation. Here, we review the methods to study macropinocytosis, describe our current knowledge of the regulatory mechanisms of antigen uptake via macropinocytosis and the intracellular trafficking route followed by macropinocytosed antigens, and discuss the significance of macropinocytosis for DC function. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Switzerland | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 237 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Poland | 1 | <1% |
| Denmark | 1 | <1% |
| Belgium | 1 | <1% |
| Unknown | 234 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 65 | 27% |
| Student > Bachelor | 39 | 16% |
| Student > Master | 26 | 11% |
| Researcher | 21 | 9% |
| Student > Doctoral Student | 14 | 6% |
| Other | 19 | 8% |
| Unknown | 53 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 48 | 20% |
| Immunology and Microbiology | 41 | 17% |
| Biochemistry, Genetics and Molecular Biology | 37 | 16% |
| Medicine and Dentistry | 20 | 8% |
| Engineering | 10 | 4% |
| Other | 23 | 10% |
| Unknown | 58 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2015.
All research outputs
#14,795,995
of 22,780,967 outputs
Outputs from Frontiers in Physiology
#5,659
of 13,561 outputs
Outputs of similar age
#199,044
of 353,036 outputs
Outputs of similar age from Frontiers in Physiology
#46
of 109 outputs
Altmetric has tracked 22,780,967 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,561 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,036 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 109 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.