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The pathophysiology of intestinal lipoprotein production

Overview of attention for article published in Frontiers in Physiology, March 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

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1 X user
wikipedia
2 Wikipedia pages

Citations

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34 Dimensions

Readers on

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119 Mendeley
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Title
The pathophysiology of intestinal lipoprotein production
Published in
Frontiers in Physiology, March 2015
DOI 10.3389/fphys.2015.00061
Pubmed ID
Authors

Antonina Giammanco, Angelo B. Cefalù, Davide Noto, Maurizio R. Averna

Abstract

Intestinal lipoprotein production is a multistep process, essential for the absorption of dietary fats and fat-soluble vitamins. Chylomicron assembly begins in the endoplasmic reticulum with the formation of primordial, phospholipids-rich particles that are then transported to the Golgi for secretion. Several classes of transporters play a role in the selective uptake and/or export of lipids through the villus enterocytes. Once secreted in the lymph stream, triglyceride-rich lipoproteins (TRLs) are metabolized by Lipoprotein lipase (LPL), which catalyzes the hydrolysis of triacylglycerols of very low density lipoproteins (VLDLs) and chylomicrons, thereby delivering free fatty acids to various tissues. Genetic mutations in the genes codifying for these proteins are responsible of different inherited disorders affecting chylomicron metabolism. This review focuses on the molecular pathways that modulate the uptake and the transport of lipoproteins of intestinal origin and it will highlight recent findings on TRLs assembly.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Austria 1 <1%
Unknown 118 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 23 19%
Student > Ph. D. Student 19 16%
Student > Bachelor 18 15%
Researcher 9 8%
Professor > Associate Professor 9 8%
Other 15 13%
Unknown 26 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 21%
Agricultural and Biological Sciences 24 20%
Medicine and Dentistry 14 12%
Pharmacology, Toxicology and Pharmaceutical Science 7 6%
Veterinary Science and Veterinary Medicine 4 3%
Other 16 13%
Unknown 29 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2020.
All research outputs
#7,212,132
of 22,796,179 outputs
Outputs from Frontiers in Physiology
#3,472
of 13,562 outputs
Outputs of similar age
#85,700
of 262,958 outputs
Outputs of similar age from Frontiers in Physiology
#29
of 110 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 13,562 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,958 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.