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X Demographics
Mendeley readers
Attention Score in Context
| Title |
NOX signaling in molecular cardiovascular mechanisms involved in the blood pressure homeostasis
|
|---|---|
| Published in |
Frontiers in Physiology, July 2015
|
| DOI | 10.3389/fphys.2015.00194 |
| Pubmed ID | |
| Authors |
Mariarosaria Santillo, Antonio Colantuoni, Paolo Mondola, Bruna Guida, Simona Damiano |
| Abstract |
Blood pressure homeostasis is maintained by several mechanisms regulating cardiac output, vascular resistances, and blood volume. At cellular levels, reactive oxygen species (ROS) signaling is involved in multiple molecular mechanisms controlling blood pressure. Among ROS producing systems, NADPH oxidases (NOXs), expressed in different cells of the cardiovascular system, are the most important enzymes clearly linked to the development of hypertension. NOXs exert a central role in cardiac mechanosensing, endothelium-dependent relaxation, and Angiotensin-II (Ang-II) redox signaling regulating vascular tone. The central role of NOXs in redox-dependent cardiovascular cell functions renders these enzymes a promising pharmacological target for the treatment of cardiovascular diseases, including hypertension. The aim of the present review is to focus on the physiological role of the cardiovascular NOX-generating ROS in the molecular and cellular mechanisms affecting blood pressure. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| United Kingdom | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 2% |
| Unknown | 94 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 17% |
| Student > Master | 14 | 15% |
| Student > Ph. D. Student | 11 | 11% |
| Student > Bachelor | 8 | 8% |
| Student > Doctoral Student | 6 | 6% |
| Other | 17 | 18% |
| Unknown | 24 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 23 | 24% |
| Biochemistry, Genetics and Molecular Biology | 17 | 18% |
| Medicine and Dentistry | 13 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Sports and Recreations | 2 | 2% |
| Other | 7 | 7% |
| Unknown | 29 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2015.
All research outputs
#17,763,547
of 22,813,792 outputs
Outputs from Frontiers in Physiology
#7,136
of 13,587 outputs
Outputs of similar age
#176,261
of 262,290 outputs
Outputs of similar age from Frontiers in Physiology
#37
of 70 outputs
Altmetric has tracked 22,813,792 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,587 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,290 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.