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Changes in Membrane Receptors and Ion Channels as Potential Biomarkers for Osteoarthritis

Overview of attention for article published in Frontiers in Physiology, December 2015
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  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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7 X users

Citations

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Title
Changes in Membrane Receptors and Ion Channels as Potential Biomarkers for Osteoarthritis
Published in
Frontiers in Physiology, December 2015
DOI 10.3389/fphys.2015.00357
Pubmed ID
Authors

Rebecca Lewis, Richard Barrett-Jolley

Abstract

Osteoarthritis (OA), a degenerative joint condition, is currently difficult to detect early enough for any of the current treatment options to be completely successful. Early diagnosis of this disease could increase the numbers of patients who are able to slow its progression. There are now several diseases where membrane protein biomarkers are used for early diagnosis. The numbers of proteins in the membrane is vast and so it is a rich source of potential biomarkers for OA but we need more knowledge of these before they can be considered practical biomarkers. How are they best measured and are they selective to OA or even certain types of OA? The first step in this process is to identify membrane proteins that change in OA. Here, we summarize several ion channels and receptors that change in OA models and/or OA patients, and may thus be considered candidates as novel membrane biomarkers of OA.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Spain 1 3%
Germany 1 3%
Unknown 31 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 15%
Student > Ph. D. Student 4 12%
Other 3 9%
Student > Doctoral Student 3 9%
Student > Master 3 9%
Other 5 15%
Unknown 11 32%
Readers by discipline Count As %
Medicine and Dentistry 6 18%
Agricultural and Biological Sciences 5 15%
Biochemistry, Genetics and Molecular Biology 4 12%
Engineering 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Other 2 6%
Unknown 12 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2015.
All research outputs
#7,679,157
of 24,834,604 outputs
Outputs from Frontiers in Physiology
#3,687
of 15,257 outputs
Outputs of similar age
#113,485
of 398,893 outputs
Outputs of similar age from Frontiers in Physiology
#49
of 134 outputs
Altmetric has tracked 24,834,604 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 15,257 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 398,893 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 134 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.