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Titin, a Central Mediator for Hypertrophic Signaling, Exercise-Induced Mechanosignaling and Skeletal Muscle Remodeling

Overview of attention for article published in Frontiers in Physiology, March 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

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32 X users
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1 Facebook page
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1 YouTube creator

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140 Mendeley
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Title
Titin, a Central Mediator for Hypertrophic Signaling, Exercise-Induced Mechanosignaling and Skeletal Muscle Remodeling
Published in
Frontiers in Physiology, March 2016
DOI 10.3389/fphys.2016.00076
Pubmed ID
Authors

Martina Krüger, Sebastian Kötter

Abstract

Titin is a giant scaffold protein with multiple functions in striated muscle physiology. Due to the elastic I-band domains and the filament-like integration in the half-sarcomere titin is an important factor for sarcomere assembly and serves as an adaptable molecular spring that determines myofilament distensibility. Protein-interactions e.g., with muscle ankyrin repeat proteins or muscle LIM-protein link titin to hypertrophic signaling and via p62 and Muscle Ring Finger proteins to mechanisms that control protein quality control. This review summarizes our current knowledge on titin as a central node for exercise-induced mechanosignaling and remodeling and further highlights the pathophysiological implications.

X Demographics

X Demographics

The data shown below were collected from the profiles of 32 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 140 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 139 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 21%
Researcher 19 14%
Student > Master 13 9%
Student > Bachelor 11 8%
Student > Doctoral Student 9 6%
Other 30 21%
Unknown 28 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 38 27%
Sports and Recreations 23 16%
Agricultural and Biological Sciences 14 10%
Medicine and Dentistry 13 9%
Engineering 5 4%
Other 13 9%
Unknown 34 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2023.
All research outputs
#2,102,698
of 25,197,939 outputs
Outputs from Frontiers in Physiology
#1,164
of 15,494 outputs
Outputs of similar age
#32,769
of 304,775 outputs
Outputs of similar age from Frontiers in Physiology
#14
of 131 outputs
Altmetric has tracked 25,197,939 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,494 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,775 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.