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Hypertension Does Not Alter the Increase in Cardiac Baroreflex Sensitivity Caused by Moderate Cold Exposure

Overview of attention for article published in Frontiers in Physiology, June 2016
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Title
Hypertension Does Not Alter the Increase in Cardiac Baroreflex Sensitivity Caused by Moderate Cold Exposure
Published in
Frontiers in Physiology, June 2016
DOI 10.3389/fphys.2016.00204
Pubmed ID
Authors

Heidi E. Hintsala, Antti M. Kiviniemi, Mikko P. Tulppo, Heta Helakari, Hannu Rintamäki, Matti Mäntysaari, Karl-Heinz Herzig, Sirkka Keinänen-Kiukaanniemi, Jouni J. K. Jaakkola, Tiina M. Ikäheimo

Abstract

Exposure to cold increases blood pressure and may contribute to higher wintertime cardiovascular morbidity and mortality in hypertensive people, but the mechanisms are not well-established. While hypertension does not alter responses of vagally-mediated heart rate variability to cold, it is not known how hypertension modifies baroreflex sensitivity (BRS) and blood pressure variability during cold exposure. Our study assessed this among untreated hypertensive men during short-term exposure comparable to habitual winter time circumstances in subarctic areas. We conducted a population-based recruitment of 24 untreated hypertensive and 17 men without hypertension (age 55-65 years) who underwent a whole-body cold exposure (-10°C, wind 3 m/s, winter clothes, 15 min, standing). Electrocardiogram and continuous blood pressure were measured to compute spectral powers of systolic blood pressure and heart rate variability at low (0.04-0.15 Hz) and high frequency (0.15-0.4 Hz) and spontaneous BRS at low frequency (LF). Comparable increases in BRS were detected in hypertensive men, from 2.6 (2.0, 4.2) to 3.8 (2.5, 5.1) ms/mmHg [median (interquartile range)], and in control group, from 4.3 (2.7, 5.0) to 4.4 (3.1, 7.1) ms/mmHg. Instead, larger increase (p < 0.05) in LF blood pressure variability was observed in control group; response as median (interquartile range): 8 (2, 14) mmHg(2), compared with hypertensive group [0 (-13, 20) mmHg(2)]. Untreated hypertension does not disturb cardiovascular protective mechanisms during moderate cold exposure commonly occurring in everyday life. Blunted response of the estimate of peripheral sympathetic modulation may indicate higher tonic sympathetic activity and decreased sympathetic responsiveness to cold in hypertension.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 9%
Student > Doctoral Student 2 9%
Researcher 2 9%
Lecturer 1 5%
Other 1 5%
Other 4 18%
Unknown 10 45%
Readers by discipline Count As %
Medicine and Dentistry 5 23%
Nursing and Health Professions 2 9%
Environmental Science 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Social Sciences 1 5%
Other 1 5%
Unknown 11 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2022.
All research outputs
#14,578,292
of 23,351,247 outputs
Outputs from Frontiers in Physiology
#5,477
of 14,090 outputs
Outputs of similar age
#192,866
of 340,870 outputs
Outputs of similar age from Frontiers in Physiology
#64
of 166 outputs
Altmetric has tracked 23,351,247 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,090 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 58% of its peers.
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We're also able to compare this research output to 166 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.