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Hypoxic Living and Exercise Training Alter Adipose Tissue Leptin/Leptin Receptor in Rats

Overview of attention for article published in Frontiers in Physiology, November 2016
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

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20 Mendeley
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Title
Hypoxic Living and Exercise Training Alter Adipose Tissue Leptin/Leptin Receptor in Rats
Published in
Frontiers in Physiology, November 2016
DOI 10.3389/fphys.2016.00554
Pubmed ID
Authors

Yingli Lu, Lianshi Feng, Minhao Xie, Li Zhang, Jianfang Xu, Zihong He, Tongjian You

Abstract

Background: Hypobaric hypoxia results in weight loss in obese individuals, and exercise training is advocated for the treatment of obesity and its related metabolic dysfunctions. The purpose of this study was to investigate the effects of hypoxic living and exercise training on obesity and adipose tissue leptin/leptin receptor in dietary-induced obese rats. Methods: One hundred and thirty high-fat diet fed Sprague-Dawley rats were assigned into one of the following groups (n = 10 each): control, sedentary hypoxic living for 1-4 weeks (SH1, SH2, SH3, and SH4), living, and exercise training in normoxic conditions for 1-4 weeks (TN1, TN2, TN3, and TN4), and living and exercise training in hypoxic conditions for 1-4 weeks (TN1, TN2, TN3, and TN4). Epididymal adipose tissue expression levels of leptin and leptin receptor were determined Results: Compared to hypoxic living and living and exercise training in normoxic conditions, living and exercise training in hypoxic conditions for 3-4 weeks resulted in lower Lee index (P < 0.05-0.01), and higher expression of leptin and leptin receptor (P < 0.05-0.01) in adipose tissue. Conclusion: In a rodent model of altitude training, living, and exercise training in hypoxic conditions resulted in greater alterations in obesity and adipose tissue leptin/leptin receptor than hypoxic living alone and living and exercise training in normoxic conditions.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 20%
Student > Ph. D. Student 3 15%
Other 2 10%
Student > Master 2 10%
Student > Bachelor 1 5%
Other 3 15%
Unknown 5 25%
Readers by discipline Count As %
Sports and Recreations 6 30%
Social Sciences 2 10%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Computer Science 1 5%
Nursing and Health Professions 1 5%
Other 2 10%
Unknown 7 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2016.
All research outputs
#6,697,756
of 24,717,692 outputs
Outputs from Frontiers in Physiology
#3,075
of 15,186 outputs
Outputs of similar age
#114,019
of 425,192 outputs
Outputs of similar age from Frontiers in Physiology
#54
of 205 outputs
Altmetric has tracked 24,717,692 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 15,186 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 425,192 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 205 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.