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Genetic Regulation of Endothelial Vasomotor Function

Overview of attention for article published in Frontiers in Physiology, November 2016
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1 X user

Citations

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Title
Genetic Regulation of Endothelial Vasomotor Function
Published in
Frontiers in Physiology, November 2016
DOI 10.3389/fphys.2016.00571
Pubmed ID
Authors

Seung Kyum Kim, Michael P. Massett

Abstract

The endothelium plays an important role in the regulation of vasomotor tone and the maintenance of vascular integrity. Endothelial dysfunction, i.e., impaired endothelial dependent dilation, is a fundamental component of the pathogenesis of cardiovascular disease. Although endothelial dysfunction is associated with a number of cardiovascular disease risk factors, those risk factors are not the only determinants of endothelial dysfunction. Despite knowing many molecules involved in endothelial signaling pathways, the genetic contribution to endothelial function has yet to be fully elucidated. This mini-review summarizes current evidence supporting the genetic contribution to endothelial vasomotor function. Findings from population-based studies, association studies for candidate genes, and unbiased large genomic scale studies in humans and rodent models are discussed. A brief synopsis of the current studies addressing the genetic regulation of endothelial responses to exercise training is also included.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 19%
Lecturer 3 11%
Professor > Associate Professor 3 11%
Student > Ph. D. Student 3 11%
Other 2 7%
Other 6 22%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 7 26%
Nursing and Health Professions 3 11%
Agricultural and Biological Sciences 3 11%
Immunology and Microbiology 2 7%
Sports and Recreations 2 7%
Other 4 15%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2016.
All research outputs
#20,355,479
of 22,903,988 outputs
Outputs from Frontiers in Physiology
#9,425
of 13,694 outputs
Outputs of similar age
#349,453
of 415,669 outputs
Outputs of similar age from Frontiers in Physiology
#149
of 217 outputs
Altmetric has tracked 22,903,988 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,694 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 415,669 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 217 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.