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Investigation of a Micro-test for Circulatory Autonomic Nervous System Responses

Overview of attention for article published in Frontiers in Physiology, July 2017
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Title
Investigation of a Micro-test for Circulatory Autonomic Nervous System Responses
Published in
Frontiers in Physiology, July 2017
DOI 10.3389/fphys.2017.00448
Pubmed ID
Authors

Maximilian Moser, Matthias Frühwirth, Dietmar Messerschmidt, Nandu Goswami, Leopold Dorfer, Frank Bahr, Gerhard Opitz

Abstract

Aims and Objectives: The autonomic nervous system plays an important role in homeostasis and organismic recreation, control of immune function, inflammation, and bone growth. It also regulates blood pressure and orthostasis via vagal and sympathetic pathways. Besides recording of heart rate variability (HRV), which characterizes medium (1-5 min) and long term (circadian) autonomic tone or modulation, no gentle tests of short-term autonomic reactivity and control are available. In 1976 Nogier described a short time cardiovascular response ("Réflexe Auriculo Cardiaque", RAC) which could be used to investigate short term autonomic reactions without changing system characteristics and thus being repeatable in short intervals. In this paper, we investigated the possible application of the Nogier reaction as a micro-test for the identification of a disturbed sensitivity or reactivity of the autonomic nervous system. Methods: We statistically analyzed cardiovascular signals derived during the application of small repeated stimuli utilizing methods of signal averaging to characterize the physiological background. Specifically, the Nogier reaction was investigated using simultaneous recordings of ECG, pulse waves, and respiration. Results: Significant fast (delay 1-5 s) and slower (delay 6-12 s) cardio-autonomic responses to different stimuli which characterize short term were observed. From time characteristics and type of signals where they occur we deduce that fast changes observed in heart rate are vagal reactions to the small stimuli whereas slower changes observed in pulse waves stem from sympathetic nervous system responses. Conclusions: The investigated autonomic micro-test opens the possibility to differentially investigate both limbs of the autonomic nervous system with minimal stimuli. It can be performed within seconds and does not change the set point of the system in opposition to less subtle tests such as Valsalva maneuver. Therefore, it is well-suited for quick, repeated measurements of autonomic nervous system reactivity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 19%
Student > Bachelor 6 14%
Researcher 5 12%
Student > Ph. D. Student 4 10%
Other 2 5%
Other 6 14%
Unknown 11 26%
Readers by discipline Count As %
Medicine and Dentistry 13 31%
Nursing and Health Professions 4 10%
Engineering 3 7%
Sports and Recreations 3 7%
Biochemistry, Genetics and Molecular Biology 2 5%
Other 4 10%
Unknown 13 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2017.
All research outputs
#14,073,810
of 22,990,068 outputs
Outputs from Frontiers in Physiology
#4,934
of 13,740 outputs
Outputs of similar age
#168,745
of 314,579 outputs
Outputs of similar age from Frontiers in Physiology
#115
of 272 outputs
Altmetric has tracked 22,990,068 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,740 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,579 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 272 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.