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Oxidative Stress in Oral Diseases: Understanding Its Relation with Other Systemic Diseases

Overview of attention for article published in Frontiers in Physiology, September 2017
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Title
Oxidative Stress in Oral Diseases: Understanding Its Relation with Other Systemic Diseases
Published in
Frontiers in Physiology, September 2017
DOI 10.3389/fphys.2017.00693
Pubmed ID
Authors

Jaya Kumar, Seong Lin Teoh, Srijit Das, Pasuk Mahakknaukrauh

Abstract

Oxidative stress occurs in diabetes, various cancers, liver diseases, stroke, rheumatoid arthritis, chronic inflammation, and other degenerative diseases related to the nervous system. The free radicals have deleterious effect on various organs of the body. This is due to lipid peroxidation and irreversible protein modification that leads to cellular apoptosis or programmed cell death. During recent years, there is a rise in the oral diseases related to oxidative stress. Oxidative stress in oral disease is related to other systemic diseases in the body such as periodontitis, cardiovascular, pancreatic, gastric, and liver diseases. In the present review, we discuss the various pathways that mediate oxidative cellular damage. Numerous pathways mediate oxidative cellular damage and these include caspase pathway, PERK/NRF2 pathway, NADPH oxidase 4 pathways and JNK/mitogen-activated protein (MAP) kinase pathway. We also discuss the role of inflammatory markers, lipid peroxidation, and role of oxygen species linked to oxidative stress. Knowledge of different pathways, role of inflammatory markers, and importance of low-density lipoprotein, fibrinogen, creatinine, nitric oxide, nitrates, and highly sensitive C-reactive proteins may be helpful in understanding the pathogenesis and plan better treatment for oral diseases which involve oxidative stress.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 180 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 180 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 13%
Student > Master 24 13%
Researcher 20 11%
Student > Bachelor 13 7%
Student > Postgraduate 9 5%
Other 36 20%
Unknown 54 30%
Readers by discipline Count As %
Medicine and Dentistry 68 38%
Biochemistry, Genetics and Molecular Biology 12 7%
Agricultural and Biological Sciences 6 3%
Immunology and Microbiology 5 3%
Pharmacology, Toxicology and Pharmaceutical Science 5 3%
Other 22 12%
Unknown 62 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2018.
All research outputs
#17,915,942
of 23,002,898 outputs
Outputs from Frontiers in Physiology
#7,231
of 13,760 outputs
Outputs of similar age
#226,874
of 316,254 outputs
Outputs of similar age from Frontiers in Physiology
#164
of 286 outputs
Altmetric has tracked 23,002,898 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,760 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,254 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 286 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.