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Mendeley readers
Attention Score in Context
| Title |
Stem Cells from Dental Pulp: What Epigenetics Can Do with Your Tooth
|
|---|---|
| Published in |
Frontiers in Physiology, December 2017
|
| DOI | 10.3389/fphys.2017.00999 |
| Pubmed ID | |
| Authors |
Beatriz A. Rodas-Junco, Michel Canul-Chan, Rafael A. Rojas-Herrera, Clelia De-la-Peña, Geovanny I. Nic-Can |
| Abstract |
Adult stem cells have attracted scientific attention because they are able to self-renew and differentiate into several specialized cell types. In this context, human dental tissue-derived mesenchymal stem cells (hDT-MSCs) have emerged as a possible solution for repairing or regenerating damaged tissues. These cells can be isolated from primary teeth that are naturally replaced, third molars, or other dental tissues and exhibit self-renewal, a high proliferative rate and a great multilineage potential. However, the cellular and molecular mechanisms that determine lineage specification are still largely unknown. It is known that a change in cell fate requires the deletion of existing transcriptional programs, followed by the establishment of a new developmental program to give rise to a new cell lineage. Increasing evidence indicates that chromatin structure conformation can influence cell fate. In this way, reversible chemical modifications at the DNA or histone level, and combinations thereof can activate or inactivate cell-type-specific gene sequences, giving rise to an alternative cell fates. On the other hand, miRNAs are starting to emerge as a possible player in establishing particular somatic lineages. In this review, we discuss two new and promising research fields in medicine and biology, epigenetics and stem cells, by summarizing the properties of hDT-MSCs and highlighting the recent findings on epigenetic contributions to the regulation of cellular differentiation. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 94 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 17% |
| Student > Ph. D. Student | 9 | 10% |
| Student > Master | 9 | 10% |
| Student > Doctoral Student | 7 | 7% |
| Researcher | 5 | 5% |
| Other | 13 | 14% |
| Unknown | 35 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 23% |
| Biochemistry, Genetics and Molecular Biology | 13 | 14% |
| Agricultural and Biological Sciences | 4 | 4% |
| Nursing and Health Professions | 3 | 3% |
| Materials Science | 2 | 2% |
| Other | 7 | 7% |
| Unknown | 43 | 46% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2019.
All research outputs
#6,866,513
of 23,011,300 outputs
Outputs from Frontiers in Physiology
#3,229
of 13,760 outputs
Outputs of similar age
#135,693
of 439,989 outputs
Outputs of similar age from Frontiers in Physiology
#87
of 322 outputs
Altmetric has tracked 23,011,300 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 13,760 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,989 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 322 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.