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Obesity, Fat Mass and Immune System: Role for Leptin

Overview of attention for article published in Frontiers in Physiology, June 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

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154 X users
facebook
2 Facebook pages
video
1 YouTube creator

Citations

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291 Dimensions

Readers on

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463 Mendeley
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Title
Obesity, Fat Mass and Immune System: Role for Leptin
Published in
Frontiers in Physiology, June 2018
DOI 10.3389/fphys.2018.00640
Pubmed ID
Authors

Vera Francisco, Jesús Pino, Victor Campos-Cabaleiro, Clara Ruiz-Fernández, Antonio Mera, Miguel A. Gonzalez-Gay, Rodolfo Gómez, Oreste Gualillo

Abstract

Obesity is an epidemic disease characterized by chronic low-grade inflammation associated with a dysfunctional fat mass. Adipose tissue is now considered an extremely active endocrine organ that secretes cytokine-like hormones, called adipokines, either pro- or anti-inflammatory factors bridging metabolism to the immune system. Leptin is historically one of most relevant adipokines, with important physiological roles in the central control of energy metabolism and in the regulation of metabolism-immune system interplay, being a cornerstone of the emerging field of immunometabolism. Indeed, leptin receptor is expressed throughout the immune system and leptin has been shown to regulate both innate and adaptive immune responses. This review discusses the latest data regarding the role of leptin as a mediator of immune system and metabolism, with particular emphasis on its effects on obesity-associated metabolic disorders and autoimmune and/or inflammatory rheumatic diseases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 154 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 463 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 463 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 58 13%
Student > Ph. D. Student 57 12%
Student > Bachelor 56 12%
Researcher 45 10%
Student > Doctoral Student 25 5%
Other 74 16%
Unknown 148 32%
Readers by discipline Count As %
Medicine and Dentistry 86 19%
Biochemistry, Genetics and Molecular Biology 83 18%
Immunology and Microbiology 26 6%
Agricultural and Biological Sciences 25 5%
Nursing and Health Professions 19 4%
Other 60 13%
Unknown 164 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 94. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2022.
All research outputs
#463,931
of 25,844,815 outputs
Outputs from Frontiers in Physiology
#251
of 15,737 outputs
Outputs of similar age
#10,028
of 344,144 outputs
Outputs of similar age from Frontiers in Physiology
#16
of 489 outputs
Altmetric has tracked 25,844,815 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,737 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,144 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 489 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.