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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Brain Natriuretic Peptide and Its Biochemical, Analytical, and Clinical Issues in Heart Failure: A Narrative Review
|
|---|---|
| Published in |
Frontiers in Physiology, June 2018
|
| DOI | 10.3389/fphys.2018.00692 |
| Pubmed ID | |
| Authors |
Shihui Fu, Ping Ping, Qiwei Zhu, Ping Ye, Leiming Luo |
| Abstract |
Heart failure (HF) is a primary cause of morbidity and mortality worldwide. As the most widely studied and commonly applied natriuretic peptide (NP), B-type natriuretic peptide (BNP) has the effects of diuresis, natriuresis, vasodilation, anti-hypertrophy, and anti-fibrosis and it inhibits the renin-angiotensin-aldosterone and sympathetic nervous systems to maintain cardiorenal homeostasis and counteract the effects of HF. Both BNP and N-terminal pro B-type natriuretic peptide (NT-proBNP) are applied as diagnostic, managing, and prognostic tools for HF. However, due to the complexity of BNP system, the diversity of BNP forms and the heterogeneity of HF status, there are biochemical, analytical, and clinical issues on BNP not fully understood. Current immunoassays cross-react to varying degrees with pro B-type natriuretic peptide (proBNP), NT-proBNP and various BNP forms and cannot effectively differentiate between these forms. Moreover, current immunoassays have different results and may not accurately reflect cardiac function. It is essential to design assays that can recognize specific forms of BNP, NT-proBNP, and proBNP to obtain more clinical information. Not only the processing of proBNP (corin/furin) and BNP (neprilysin), but also the effects of glycosylation on proBNP processing and BNP assays, should be targeted in future studies to enhance their diagnostic, therapeutic, and prognostic values. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 33% |
| Switzerland | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 101 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 13 | 13% |
| Student > Master | 11 | 11% |
| Researcher | 9 | 9% |
| Student > Postgraduate | 9 | 9% |
| Student > Ph. D. Student | 6 | 6% |
| Other | 12 | 12% |
| Unknown | 41 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 31% |
| Biochemistry, Genetics and Molecular Biology | 7 | 7% |
| Agricultural and Biological Sciences | 5 | 5% |
| Veterinary Science and Veterinary Medicine | 3 | 3% |
| Chemistry | 3 | 3% |
| Other | 10 | 10% |
| Unknown | 42 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2023.
All research outputs
#17,284,057
of 25,382,035 outputs
Outputs from Frontiers in Physiology
#7,582
of 15,597 outputs
Outputs of similar age
#217,713
of 336,975 outputs
Outputs of similar age from Frontiers in Physiology
#272
of 497 outputs
Altmetric has tracked 25,382,035 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 15,597 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,975 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 497 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.