You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events
|
|---|---|
| Published in |
Frontiers in Physiology, July 2018
|
| DOI | 10.3389/fphys.2018.00806 |
| Pubmed ID | |
| Authors |
Cristina Carvalho, Paula I. Moreira |
| Abstract |
The brain is one of the most exquisite organs in the body with high metabolic demands, and requires a tight regulation of the surrounding environment. This tight control is exerted by the neurovascular unit (NVU) comprising different cell types, where endothelial cells play the commander-in-chief role. Thus, it is assumable that even slight perturbations in NVU might affect, in some cases irreversibly, brain homeostasis and health. In this line, recent findings support the two-hit vascular hypothesis for neurodegenerative conditions, where vascular dysfunction underlies the development of neurodegenerative diseases, such as Alzheimer's disease (AD). Knowing that endothelial cells are rich in mitochondria and nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, two major reactive oxygen species (ROS) sources, this review aims to gather information on how oxidative stress is in the front line of vascular alterations observed in brain aging and neurodegenerative conditions, particularly AD. Also, a brief discussion about the therapeutic strategies aimed to protect against cerebrovascular diseases is included. |
X Demographics
The data shown below were collected from the profiles of 41 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 5 | 12% |
| Brazil | 3 | 7% |
| United States | 3 | 7% |
| Colombia | 2 | 5% |
| Venezuela, Bolivarian Republic of | 2 | 5% |
| Switzerland | 2 | 5% |
| Argentina | 2 | 5% |
| Senegal | 1 | 2% |
| Egypt | 1 | 2% |
| Other | 7 | 17% |
| Unknown | 13 | 32% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 34 | 83% |
| Scientists | 6 | 15% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 150 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 15% |
| Student > Master | 21 | 14% |
| Student > Bachelor | 21 | 14% |
| Researcher | 17 | 11% |
| Student > Postgraduate | 6 | 4% |
| Other | 19 | 13% |
| Unknown | 44 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 25 | 17% |
| Medicine and Dentistry | 19 | 13% |
| Agricultural and Biological Sciences | 13 | 9% |
| Neuroscience | 12 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 7% |
| Other | 20 | 13% |
| Unknown | 51 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2020.
All research outputs
#1,182,587
of 24,662,675 outputs
Outputs from Frontiers in Physiology
#652
of 15,161 outputs
Outputs of similar age
#25,568
of 333,054 outputs
Outputs of similar age from Frontiers in Physiology
#53
of 517 outputs
Altmetric has tracked 24,662,675 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,161 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,054 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 517 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.