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The Shape Shifting Story of Reticulocyte Maturation

Overview of attention for article published in Frontiers in Physiology, July 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

twitter
4 X users
wikipedia
1 Wikipedia page

Citations

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51 Dimensions

Readers on

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122 Mendeley
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Title
The Shape Shifting Story of Reticulocyte Maturation
Published in
Frontiers in Physiology, July 2018
DOI 10.3389/fphys.2018.00829
Pubmed ID
Authors

Elina Ovchynnikova, Francesca Aglialoro, Marieke von Lindern, Emile van den Akker

Abstract

The final steps of erythropoiesis involve unique cellular processes including enucleation and reorganization of membrane proteins and the cytoskeleton to produce biconcave erythrocytes. Surprisingly this process is still poorly understood. In vitro erythropoiesis protocols currently produce reticulocytes rather than biconcave erythrocytes. In addition, immortalized lines and iPSC-derived erythroid cell suffer from low enucleation and suboptimal final maturation potential. In light of the increasing prospect to use in vitro produced erythrocytes as (personalized) transfusion products or as therapeutic delivery agents, the mechanisms driving this last step of erythropoiesis are in dire need of resolving. Here we review the elusive last steps of reticulocyte maturation with an emphasis on protein sorting during the defining steps of reticulocyte formation during enucleation and maturation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 122 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 15%
Student > Ph. D. Student 18 15%
Student > Bachelor 16 13%
Student > Master 14 11%
Other 5 4%
Other 11 9%
Unknown 40 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 34 28%
Medicine and Dentistry 14 11%
Agricultural and Biological Sciences 12 10%
Immunology and Microbiology 4 3%
Pharmacology, Toxicology and Pharmaceutical Science 3 2%
Other 12 10%
Unknown 43 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2021.
All research outputs
#6,361,124
of 25,653,515 outputs
Outputs from Frontiers in Physiology
#2,869
of 15,711 outputs
Outputs of similar age
#99,747
of 340,222 outputs
Outputs of similar age from Frontiers in Physiology
#146
of 507 outputs
Altmetric has tracked 25,653,515 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,711 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,222 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 507 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.