Title |
Cysteine–based redox regulation and signaling in plants
|
---|---|
Published in |
Frontiers in Plant Science, January 2013
|
DOI | 10.3389/fpls.2013.00105 |
Pubmed ID | |
Authors |
Jérémy Couturier, Kamel Chibani, Jean-Pierre Jacquot, Nicolas Rouhier |
Abstract |
Living organisms are subjected to oxidative stress conditions which are characterized by the production of reactive oxygen, nitrogen, and sulfur species. In plants as in other organisms, many of these compounds have a dual function as they damage different types of macromolecules but they also likely fulfil an important role as secondary messengers. Owing to the reactivity of their thiol groups, some protein cysteine residues are particularly prone to oxidation by these molecules. In the past years, besides their recognized catalytic and regulatory functions, the modification of cysteine thiol group was increasingly viewed as either protective or redox signaling mechanisms. The most physiologically relevant reversible redox post-translational modifications (PTMs) are disulfide bonds, sulfenic acids, S-glutathione adducts, S-nitrosothiols and to a lesser extent S-sulfenyl-amides, thiosulfinates and S-persulfides. These redox PTMs are mostly controlled by two oxidoreductase families, thioredoxins and glutaredoxins. This review focuses on recent advances highlighting the variety and physiological roles of these PTMs and the proteomic strategies used for their detection. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | <1% |
France | 1 | <1% |
Uruguay | 1 | <1% |
Austria | 1 | <1% |
Sweden | 1 | <1% |
United Kingdom | 1 | <1% |
Slovenia | 1 | <1% |
Belgium | 1 | <1% |
Unknown | 168 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 34 | 19% |
Researcher | 34 | 19% |
Student > Master | 20 | 11% |
Student > Doctoral Student | 14 | 8% |
Student > Bachelor | 12 | 7% |
Other | 27 | 15% |
Unknown | 35 | 20% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 33 | 19% |
Environmental Science | 5 | 3% |
Chemistry | 4 | 2% |
Medicine and Dentistry | 4 | 2% |
Other | 7 | 4% |
Unknown | 42 | 24% |